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Table 2 Clinical and laboratory details of patients with possible BSI

From: In-depth analysis of T2Bacteria positive results in patients with concurrent negative blood culture: a case series

Demographics

Age range, Gender

Brief History of present illness

T2Bacteria result

Other (+) culture with pathogen different than T2-detected within 21 days

Antibiotics used/Activity against T2 detected bacterium (% susceptibility)

Radiologic Findings

Discharge Diagnosis

Patient 12

18–49, F

Chest pain, fever, hypoxemia, and tachycardia. Active Cocaine/Heroin IV user, HCV, recent dental surgery.

S. aureus

No

VAN, AZM, TZP/ (VAN-100%)

CT: c/w pneumonia. TTE was negative

Pneumonia

Patient 13

> 65, F

Sudden onset left sided abdominal pain, nausea, vomiting.

P. aeruginosa

No

CIP, MTZ / (CIP-85%)

i) CT (day 1): Acute uncomplicated diverticulitis ii) CT (day 3): Minimally complicated diverticulitis with micro-perforation, as well as new secondary enteritis and small bowel obstruction

Diverticulitis

Patient 14

18–49, F

Fever, tachycardia, nausea, vomiting. Diagnosed with breast cancer, on Trastuzumab (had chest port site).

E. coli

BC from port site yielded CoNS (−1d) (considered contaminant)

VAN, FEP / (FEP-98%)

Sepsis without clear source identified

Patient 15

18–49, M

Abdominal pain, fever, nausea after appendectomy (Postoperative day 4). Reported a sharp RLQ pain and ecchymosis surrounding his incisions.

P. aeruginosa

Culture of drainage from right lower quadrant collection yielded E. coli and Clostridium species

TZP / (TZP-91%)

CT: Right lower quadrant collection compatible with a postoperative hematoma with possible superinfection

Infected postoperative hematoma

  1. AZM Azithromycin, CIP Ciprofloxacin, CFZ Cefazolin, CoNS Coagulase-negative Staphylococcus, CT Computed Tomography, c/w compatible with, F Female, FEP Cefepime, M Male, MEM Meropenem, MTZ Metronidazole, TTE Transthoracic Echocardiogram, TZP Piperacillin-Tazobactam, UTI Urinary tract infection, VAN Vancomycin