Table 1 Laboratory investigation timeline and reports (abnormal values are marked in bold)
From: Scrub typhus as a rare cause of acute pyelonephritis: case report
Laboratory parameters | Normal values (KMC Lab protocol) | Day 1 | Day 4 | Day 5 | Day 6 | Day 7 (Doxycycline added) | Day 8 | Day 10 | Day 17 |
|---|---|---|---|---|---|---|---|---|---|
Hematology | |||||||||
TC (cells/mm3) | 3500-10,500 | 10,700 | 14,800 | 12,200 | 11,100 | 11,400 | 12,500 | 12,400 | 7400 |
DC (%) | N60–80, L20–30, E1–4 | N82 L13 | N66 L24 E10 | N83 L15 | N87 L12 | N80 L17 | N71 L27 | N73 L22 | N67 L26 |
Hb (gm/dL) | 12–16 | 13.4 | 13.7 | 11.0 | 10.8 | 10.4 | 11.2 | 10.7 | 11.7 |
Platelets (cells/mm3) | 150,000-450,000 | 192,000 | 190,000 | 115,000 | 120,000 | 145,000 | 212,000 | 232,000 | 490,000 |
ESR (mm/hr) | < 15 | 41 | |||||||
Renal panel | |||||||||
Urea (mg/dL) | 15–45 | 29 | 30 | 25 | 22 | 29 | 18 | 33 | 33 |
Creatinine (mg/dL) | 0.5–1.2 | 1.0 | 1.5 | 1.3 | 1.2 | 1.2 | 1.0 | 1.0 | 0.9 |
Sodium (mmol/L) | 135–145 | 138 | 135 | 136 | 136 | 136 | 138 | 138 | 142 |
Potassium (mmol/L) | 3.5–5.0 | 3.7 | 3.8 | 3.8 | 3.4 | 3.1 | 3.5 | 3.5 | 4.8 |
Liver panel | |||||||||
Total Bilirubin mg/dL) | 0.2–1.2 | 1.7 | |||||||
Direct Bilirubin (mg/dL) | 0–0.4 | 1.0 | |||||||
SGPT/SGOT (IU/L) | < 45 each | 32/16 | |||||||
ALP (IU/L) | 50–100 | 521 | |||||||
Albumin (gm/dL) | 3.5–5.0 | ||||||||
PT/INR (sec) | 11.0–13.5/ 0.8–1.2 | 15.0/1.17 | |||||||
Urine examination | |||||||||
Urine pus cells (per hpf) | < 1–2 | 10–12 | plenty | 0–2 | |||||
Urine RBC | nil | nil | nil | ||||||
Urine albumin | nil | nil | nil | ||||||
Urine culture | no growth | no growth | no growth | ||||||
Other blood tests | |||||||||
Random sugar (mg/dL) | 60–140 | 99 | 81 | ||||||
Serum Lipase/Amylase (U/L) | 10–160/ 25–110 | 15/25 | |||||||
Blood culture | no growth | ||||||||
Tropical panel serology | |||||||||
Scrub typhus | positive (rapid IgM) | ||||||||
Leptospira | negative | ||||||||
Dengue | negative | ||||||||
Leishmaniasis | negative | ||||||||
Malaria (optimal test) | negative | ||||||||