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Table 4 Description of trends in antibiotic prescribing among patients with severe infections in Ujjain between 2008 and 2017

From: Antibiotic prescribing among patients with severe infectious diseases in two private sector hospitals in Central India – a time series analysis over 10 years

 

NTH

TH

Antibiotic prescribing among specific diagnoses

 All antibiotics

13.84 (< 0.01)

1.82 (0.07)

 Cellulitis

5.72 (< 0.01)

6.52 (< 0.01)

 Peritonitis

14.59 (< 0.01)

18.52 (< 0.01)

 Pneumonia

4.87 (< 0.01)

7.30 (< 0.01)

 Sepsis

2.18 (0.03)

−21.91 (< 0.01)

Antibiotic prescribing among all included patients

Access antibiotics

11.52 (< 0.01)

1.78 (< 0.07)

Watch antibiotics

9.63 (< 0.01)

6.49 (< 0.01)

Reserve antibiotics

−0.76 (0.45)

2.54 (< 0.01)

 FDCs of antibiotics

14.28 (< 0.01)

7.31 (< 0.01)

Antibiotic prescribing among sepsis patients

Access antibiotics

1.49 (0.14)

−16.89 (< 0.01)

Watch antibiotics

3.02 (< 0.01)

−11.38 (< 0.01)

Reserve antibiotics

−9.32 (< 0.01)

Too few prescriptions

 FDCs of antibiotics

3.78 (< 0.01)

−9.93 (< 0.01)

  1. Notes: All values are presented with a value for the slope: t, followed by P-value in parenthesis. The t-value is obtained from linear regression analysis and indicates a postitive or negative trend of antibiotic prescribing (measured in DDDs per 1000 patients), over the study period. A positive t-value shows a positive trend of antibiotic prescribing during the study period and a negative t-value shows a negative trend of antibiotic prescribing during the study period. Statistically significant p-values indicates a significant trend and are marked in bold font
  2. Abbreviations: DDD Defined daily dosis, FDC Fixed dose combination, NTH Non-teaching hospital, TH Teaching hospital