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Table 5 Antibiotics prescribed among patients with severe infections at two private sector hospitals from 2007 to 2018

From: Antibiotic prescribing among patients with severe infectious diseases in two private sector hospitals in Central India – a time series analysis over 10 years

 Antibiotic prescribing in DDDs per 1000 patient days%Slope, taP-value
Year2008200920102011201220132014201520162017   
Cellulitis NTH
J01CR4.124.440.734.783.174.905.774.333.247.11162.320.02
J01D13.119.011.9811.525.094.2812.507.5414.183.06326.33< 0.01
J01R6.535.603.122.604.703.463.016.786.121.84176.97< 0.01
J01X9.2515.763.683.341.301.051.621.081.421.48153.31< 0.01
Cellulitis TH
J01CR10.847.454.247.149.478.9910.078.0316.2913.33194.91< 0.01
J01D4.486.019.326.224.764.666.876.539.982.10125.58< 0.01
J01G9.3313.539.119.2614.5510.4710.016.3715.645.45210.440.66
J01M10.208.703.355.669.004.514.303.319.116.22132.66< 0.01
J01X6.533.707.386.506.8610.227.893.849.173.91132.270.02
Peritonitis NTH
J01CR3.714.263.8510.233.065.704.455.895.674.40164.98< 0.01
J01D26.286.434.544.3410.367.351.417.788.045.06251.340.18
J01R8.586.145.295.555.011.143.095.026.191.40158.67< 0.01
J01X16.0311.7211.649.094.572.491.581.813.541.972010.95< 0.01
Peritonitis TH
J01CR5.844.396.685.5510.929.1316.5413.4413.365.351510.16< 0.01
J01D4.004.959.639.446.872.766.047.6415.877.731217.55< 0.01
J01G10.084.6511.089.9411.846.4911.4311.878.644.08158.13< 0.01
J01M16.0510.723.276.4011.995.8311.6012.8615.423.56162.92< 0.01
J01X15.759.5516.8517.7315.4413.9222.6417.3023.055.24268.69< 0.01
Pneumonia NTH
J01CR11.545.014.054.274.954.615.965.798.798.1729−0.910.36
J01D7.756.924.228.533.242.951.374.444.234.1822−1.380.17
J01M1.000.490.470.502.410.833.987.343.471.18102.540.01
J01R5.744.613.512.554.214.765.274.613.724.82205.65< 0.01
Pneumonia TH
J01A16.4411.8514.238.4513.7610.187.212.912.2518.79251.810.07
J01CR8.4512.6410.661.918.2615.7120.0219.2115.3813.27306.65< 0.01
J01D3.856.015.0410.917.244.653.943.8115.3120.741912.87< 0.01
J01M15.879.368.725.723.882.041.611.774.657.44141.890.06
Sepsis NTH
J01CR5.053.902.131.972.232.553.016.903.476.66211.100.27
J01D10.747.471.193.274.633.864.776.374.291.7027−4.67< 0.01
J01R7.553.661.711.332.093.361.843.072.632.76173.17< 0.01
J01X12.226.544.510.990.790.001.281.020.720.0016−6.07< 0.01
Sepsis TH
J01A14.617.679.591.834.312.954.260.000.003.1311−5.50< 0.01
J01CR1.8411.1827.872.765.091.838.047.097.797.0919−5.07< 0.01
J01D1.375.488.483.035.873.7912.275.577.214.8913−5.20< 0.01
J01M11.511.7514.4511.323.130.114.750.912.813.6213−8.49< 0.01
J01X8.9512.9315.347.089.186.3612.600.916.004.0719−15.48< 0.01
  1. Notes: Antibiotics presented comprise ≥ 75% of the total antibiotic prescribing within each diagnosis group. Numbers are presented in total antibiotic prescribing of antibiotic groups for each year, measured in DDD/1000 patient days and percentage of the total prescribing of antibiotics for each diagnosis and hospitals during the study period. a t is obtained by linear regression, a positive t shows a positive trend and a negative t shows a negative trend of prescribing. Statistically significant p-values indicates a significant trend and are marked in bold font
  2. Abbreviations: DDD Defined daily doses, NTH Non-teaching hospital, TH Teaching hospital