Table 1 The correlation between serum vancomycin concentrations and characteristics of patients included in different groups
Groups | Demographics and characteristics | Case no. | Vancomycin concentration (μg/mL) | Chi-square | P-value | ||
|---|---|---|---|---|---|---|---|
< 10 | 10 ~ 20 | > 20 | |||||
Group A (age < 60 years) | Sex | 1.443 | 0.4861 | ||||
Male | 61 | 40 | 18 | 3 | |||
Female | 27 | 15 | 9 | 3 | |||
BMI (kg/m2) | 22.450 | < 0.001*** | |||||
< 24 | 36 | 12 | 19 | 5 | |||
≥ 24 | 52 | 43 | 8 | 1 | |||
CrCl (mL/min) | 8.247 | 0.0162* | |||||
< 90 | 21 | 9 | 8 | 4 | |||
≥ 90 | 67 | 46 | 19 | 2 | |||
Group B (age ≥ 60 years) | Sex | 3.206 | 0.2013 | ||||
Male | 72 | 23 | 35 | 14 | |||
Female | 44 | 8 | 23 | 13 | |||
BMI (kg/m2) | 25.360 | < 0.001*** | |||||
< 24 | 82 | 11 | 48 | 23 | |||
≥ 24 | 34 | 20 | 10 | 4 | |||
CrCl (mL/min) | 18.320 | 0.0001*** | |||||
< 90 | 74 | 10 | 43 | 21 | |||
≥ 90 | 42 | 21 | 15 | 6 | |||