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Table 2 Performances of APRI and FIB-4 in predicting cirrhosis using transient elastography as a gold standard

From: Diagnostic performance of APRI and FIB-4 for confirming cirrhosis in Indonesian HIV/HCV co-infected patients

 

APRI 1

FIB-4 1.66

Se (95% CI)

48.4% (35.7–61.2)

53.1% (40.2–65.7)

Sp (95% CI)

95.0% (90.3–97.8)

92.5% (87.1–96.0)

PPV (95% CI)

79.5% (65.3–88.8)

73.9% (61.0–83.6)

NPV (95% CI)

82.1% (78.3–85.3)

83.1% (79.0–86.4)

LR+ (95% CI)

9.6 (4.7–19.8)

7.0 (3.9–12.7)

LR- (95% CI)

0.5 (0.4–0.7)

0.5 (0.3–0.6)

Ac (95% CI)

81.6% (75.9–86.5)

81.1% (75.4–86.0)

AUC (95% CI)

0.72 (0.63–0.80)

0.73 (0.65–0.81)

  1. Se: sensitivity; Sp: specificity; PPV: positive predictive value; NPV: negative predictive value; LR-: negative likelihood ratio; LR+: positive likelihood ratio; Ac: accuracy; K: kappa; AUROC: area under the receiving operator curve