Table 1 Clinical characteristics and diagnostics for the patients with severe M. pneumoniae pneumonia
Case No. | Male | Age | Month of admission | Tmax (°C) | Cough | Dyspnea | Diarrhea | Length of onset to dyspnea (days) | Length of onset to ICU admission (days) | Ig G | IgM | PCR of sputum | PCR of BALF | PCR of pleural effusion | NGS from BALF | Combined Bacteria or virus | Length of ICU stay (days) | Length of hospital stay (days) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case 1 | Female | 34 | June | 40.6 | Dry cough | Yes | Yes | 13 | 15 | – | – | Positive | Positive | NA | Positive | Adenovirus | 14 | 14 |
Case 2 | Female | 26 | May | 40.6 | Dry cough | Yes | Yes | 12 | 14 | + | + | Positive | NA | NA | Positive | Rhinovirus Streptococcus | 7 | 20 |
Case 3 | Female | 15 | Dec. | 40.5 | Productive cough | Yes | Yes | 15 | 15 | + | + | Positive | NA | NA | NA | None | 6 | 15 |
Case 4 | Male | 42 | May | 42 | Dry cough | Yes | No | 6 | 9 | – | – | Positive | NA | NA | NA | Rhinovirus Epstein-Barr virus | 12 | 12 |
Case 5 | Male | 32 | Apr. | 39.6 | Dry cough | Yes | No | 12 | 14 | + | – | Positive | NA | NA | NA | Rhinovirus | 13 | 13 |
Case 6 | Male | 44 | Mar. | 40 | Dry cough | Yes | No | 6 | 14 | + | – | Positive | NA | NA | NA | Rhinovirus | 3 | 13 |
Case 7 | Male | 53 | Nov. | 39.5 | Productive cough | Yes | No | 9 | 10 | + | – | Positive | NA | NA | NA | None | 4 | 17 |
Case 8 | Female | 17 | Aug. | 41.2 | Dry cough | Yes | No | 5 | 12 | + | + | Positive | Positive | Positive | Positive | Acinetobacter baumannii | 33 | 33 |
Case 9 | Male | 34 | Oct.. | 39.6 | Dry cough | Yes | No | 9 | 11 | + | + | Positive | Positive | NA | Positive | None | 4 | 14 |
Case 10 | Male | 17 | Nov | 39.8 | Dry cough | Yes | Yes | 3 | 3 | – | + | NA | NA | NA | Positive | Acinetobacter baumannii | 9 | 18 |
Mean (±SD) | 6/10 (60%) | 31 (13) |  | 40.4 (0.8) |  | 10/10 (100%) | 4/10 (40%) | 9 (4) | 11 (4) | + (70%) | + (50%) | 9 | 3 | 1 | 5 |  | 11 (9) | 17 (6.2) |