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Table 3 Laboratory features of COVID-19 patients in Shiraz, South of Iran; presented as either mean ± SD, or frequency

From: Epidemiological and clinical features of 2019 novel coronavirus diseases (COVID-19) in the South of Iran

Laboratory Findings

Normal Value

All patients

n = 113

Sever

n = 11

Not Sever

n = 102

P.value

Dead

n = 9

Live

n = 104

P.value

White blood cell count

3.5–9.5

6.06 (±2.50)

6.62 (±2.68)

6.00 (±2.49)

0.438

6.83 (±2.94)

6.00 (±2.47)

0.341

 Leukopenia

10 (9)

0 (0)

10 (100)

0.424

1 (10)

9 (90)

0.484

 Normal

89 (80.2)

9 (10.1)

80 (89.9)

6 (6.7)

83 (93.3)

 Leukocytosis

12 (10.8)

2 (16.7)

10 (83.3)

2 (16.7)

10 (83.3)

Neutrophil count (a109/L)

1.8–6.3

4.60 (±2.2)

10.33 (±0)

4.37 (± 1.93)

0.006

6.49 (± 3.47)

4.26 (± 1.83)

0.064

 1.8–6.3

20 (76.9)

0 (0)

20 (100)

0.231

2 (10)

18 (90)

0.218

  > 6.3

6 (23.1)

1 (16.7)

5 (83.3)

2 (33.3)

4 (66.7)

Lymphocyte count (a109/L)

1.1–3.2

1.16 (±0.66)

1.37 (± 0.62)

1.14 (± 0.66)

0.386

1.09 (±0.64)

1.16 (±0.66)

0.791

  < 1500

14 (12.6)

4 (28.6)

10 (71.4)

0.030a

3 (21.4)

11 (78.6)

0.141

 1.5–3.2

71 (64)

4 (5.6)

53 (94.4)

4 (5.6)

67 (94.4)

  > 3.2

26 (23.4)

3 (11.5)

23 (88.5)

2 (7.7)

24 (92.3)

Monocyte count (a109/L)

0.1–0.6

0.49 (±0.34)

0.46 (± 0)

0.50 (±0.38)

0.939

0.46 (± 0)

0.50 (± 0.38)

0.939

 Normal

5 (83.3)

1 (20)

4 (80)

1.000

1 (20)

4 (80)

1.000

 Increase Monocyte count

1 (16.6)

0 (0)

1 (100)

0 (0)

1 (100)

Hemoglobin (g/L)

12–17.5

13.54 (±2.39)

13.28 (±1.53)

13.57 (±2.47)

0.706

13.02 (±2.26)

13.58 (±2.41)

0.500

Hematocrit (%)

36–54

40.42 (±4.69)

37.05 (±10.81)

40.66 (±4.29)

0.301

40.02 (±6.6)

40.50 (± 4.3)

0.838

Platelet count

150–450

220.92 (±105.66)

220 (±108.82)

220.98 (±105.87)

0.985

199.55 (±104.24)

222.85 (±106.09)

0.791

 Thrombocytopenia

17 (15.6)

2 (11.8)

15 (88.2)

0.676

1 (5.9)

16 (94.1)

0.927

 Normal

80 (73.4)

7 (8.8)

73 (91.3)

7 (8.8)

73 (91.3)

 Thrombocytosis

12 (11.0)

2 (16.7)

10 (83.3)

1 (8.3)

11 (91.7)

Prothrombin Time (S)

9.4–13.5

15.35 (±2.38)

16.30 (±2.39)

15.25 (±2.37)

0.167

16.70 (± 1.54)

15.23 (± 2.41)

0.077

 Normal

25 (22.1)

2 (8)

23 (92)

0.796

0 (0)

25 (100)

0.249

 Prolonged

88 (77.9)

9 (10.2)

79 (89.8)

9 (10.2)

79 (89.8)

Partial Thromboplastin Time (S)

25–36.5

37.61 (±8.49)

37.81 (±12.36)

37.59 (±8.02)

0.934

35.11 (± 10.48)

37.84 (± 8.31)

0.357

 Decreased

1 (0.9)

2 (100)

0 (0)

0.000a

1 (50)

1 (50)

0.100

 Normal

57 (53.3)

2 (3.6)

54 (96.4)

4 (7.1)

52 (92.9)

 Prolonged

49 (45.8)

7 (14.3)

42 (85.7)

4 (8.2)

45 (91.8)

International Normalized Ratio

0–1.1

1.32 (±0.23)

1.85 (±0.49)

1.28 (±0.15)

0.000a

1.64 (± 0.32)

1.25 (± 0.13)

0.000a

Blood urea nitrogen (mg/dL)

7–20

16.80 (±5.81)

17.34 (±6.57)

16.75 (±5.76)

0.762

17.67 (± 16.73)

16.73 (± 5.68)

0.663

  ≤ 20

82 (76.6)

8 (9.8)

74 (90.2)

1.000

6 (7.3)

76 (92.7)

1.000

  > 20

25 (23.4)

2 (8)

23 (92)

2 (8)

23 (92)

Creatinine (mg/dL)

0.6–1.2

1.13 (±0.35)

1.22 (±0.38)

1.12 (±0.35)

0.418

1.02 (±0.29)

1.14 (±0.36)

0.386

  ≤ 1.2

69 (64.5)

6 (8.7)

63 (91.3)

0.741

6 (8.7)

63 (91.3)

0.709

  > 1.2

38 (35.5)

4 (10.5)

34 (89.5)

2 (5.3)

36 (94.7)

Sodium (mmol/L)

135–145

137.7(±5.12)

137.13 (±4.53)

137.73 (±5.21)

0.717

138.91 (±5.74)

137.56 (±5.09)

0.478

Potassium (mmol/L)

3.5–5

4.1(±0.6)

3.84 (±0.46)

4.08 (±0.57)

0.195

4.34 (± 0.68)

4.04 (0.56)

0.478

Lactate dehydrogenase (U/L)

0–250

686.23 (±509.39)

–

686.23 (± 509.39)

NA

1116.5 (± 1059.95)

628.86 (± 431.66)

0.214

Aspartate aminotransferase (U/L)

15–40

47.00 (±30.86)

49.00 (± 0)

47.00 (± 33.33)

1.000

47 (± 0)

47 (± 33.33)

1.000

Alanine aminotransferase (U/L)

9–50

35.87 (±36.48)

32.00 (± 0)

36.42 (± 39.36)

0.920

32.00 (± 0)

36.42 (±39.36)

0.920

Albumin (g/L)

3.4–5.4

3.90 (±0.46)

3.90 (±0)

3.90 (±0.47)

0.986

3.90 (±0.20)

3.90 (± 0.49)

0.974

Total bilirubin (mmol/L)

0–1.4

0.69 (±0.30)

0.64 (±0)

0.69 (±0.31)

0.866

0.38 (±0.21)

0.73 (± 0.29)

0.063

Direct Bilirubin (mmol/L)

0–0.3

0.34 (±0.16)

0.31(± 0)

0.34 (±0.16)

0.846

0.23 (± 0.10)

0.35 (±0.16)

0.333

C reactive Protein (mg/L)

0–8

34.32 (±20.40)

44.00 (±24.74)

33.33 (±19.79)

0.116

35.00 (± 25.27)

34.28 (±20.23)

0.934

  < 8

9 (8.3)

0 (0)

9 (100)

0.127

0 (0)

9 (100)

0.616

 8–50

72 (66.7)

5 (6.9)

67 (93.1)

5 (6.9)

67 (93.1)

  ≥ 50

27 (25)

5 (18.5)

22 (81.5)

1 (3.7)

26 (96.3)

Erythrocyte sedimentation rate (mm/h)

0–20

45.05 (±21.93)

45.66 (±22.39)

34 (±0)

0.619

41.50 (± 24.89)

46.00 (± 21.93)

0.726

  < 20

1 (0.9)

0 (0)

1 (100)

1.000

0 (0)

1 (100)

1.000

  ≥ 20

18 (15.9)

1 (5.6)

17 (94.4)

4 (22.2)

14 (77.8)

PH

7.35–7.45

7.35 (0.29)

7.41 (±0.05)

7.33 (±0.32)

0.567

   

 Acidosis

8 (7.1)

1 (16.7)

5 (83.3)

0.727

0 (0)

6 (100)

0.394

 Normal

28 (24.8)

5 (17.9)

23 (82.1)

5 (17.9)

23 (82.1)

 Alkaline

3 (2.7)

0 (0)

3 (100)

1 (33.3)

2 (66.7)

Arterial Blood Gas

 PCO2

35–48

44.08 (±10.73)

42.45 (± 6.61)

44.26 (± 11.11)

0.615

46.20 (± 15.27)

43.89 (± 10.33)

0.563

 PO2

40

31.24(±13.74)

38.88 (±17.50)

30.35 (±13.06)

0.051

47.40 (± 27.23)

29.73 (10.83)

0.000a

 HCO3

35–48

25.62 (±3.58)

25.91 (±3.25)

25.58 (±3.63)

0.789

25.82 (± 4.35)

25.60 (± 3.53)

0.868

  1. NA: Not applicable; a indicator of significant correlation