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Table 3 Estimates and the 95% confidence intervals for parameters of multilevel ordinal non-proportional-odds model

From: Multilevel ordinal model for CD4 count trends in seroconversion among South Africa women

Effect

Non-Proportional Odds

Normal vs Mild, Advance, Severe

Normal, Mild vs Advance, Severe

Normal, Mild, Advance vs Severe

Exp (β) (95%CI)

Exp (β) (95%CI)

Exp (β) (95%CI)

Thresholds

 Normal

0.02 (0.01, 0.09)*

  

 Mild

 

19.87 (3.71, 50.4)*

 

 Advanced

  

24.51 (3.62, 81.35)*

Age: 21–39 years

3.62 (1.03, 10.41)**

3.36 (1.64, 36.99)*

4.15 (0.99, 50.32)

Age: 40–59 years

2.24 (0.75, 7.35)

1.58 (0.44, 4.81)

3.23 (0.82, 20.53)

Education: Grade 9–10

1.06 (0.17, 5.31)

0.72 (0.10, 3.77)

2.28 (0.17, 19.40)

Education: Grade  ≥11

2.13 (1.05, 12.11)*

2.07 (0.54, 11.26)

3.61 (1.03, 35.21)*

Sex while Drunk: No

3.34 (1.22, 10.63)**

5.21 (1.71, 17.08)*

2.57 (0.57, 13.71)

Weight

1.01 (0.99, 1.03)

1.02 (1.01, 1.03)*

1.02 (0.98, 1.03)

Marital status: Single/no sexual partners

3.28 (0.71, 10.27)

3.45 (0.97, 10.48)

0.57 (0.07, 5.31)

Marital status: Many sexual partners

0.88 (0.14, 4.95)

0.19 (0.01, 2.20)

0.12 (0.01, 0.19)*

cART: After initiation

1.42 (0.60, 3.33)

1.27 (1.11, 1.45)**

1.28 (1.15, 1.43)**

Physical health score

1.10 (0.99, 1.17)

1.11 (1.07, 1.18)*

1.57 (1.41, 1.62)**

Level of independence scores

1.18 (1.12, 1.27)*

1.02 (0.96, 1.18)

0.83 (0.71, 1.01)

Social relationship scores

0.96 (0.90, 1.01)

0.93 (0.88, 0.98)

0.92 (0.78, 1.11)

Psychological well-being scores

0.94 (0.81, 1.11)

0.77 (0.71, 1.81)

0.51 (0.47, 1.68)

RBC indices component

1.06 (0.91, 1.23)

0.96 (0.82, 1.10)

0.85 (0.55, 1.30)

Electrolyte component

1.11 (1.04, 1.29)*

1.09 (1.01, 1.18)*

0.99 (0.77, 1.27)

Mononuclear component

1.73 (1.48, 2.05)*

1.79 (1.51, 2.12)*

2.14 (0.98, 3.49)

Viral Load

0.52 (0.41, 0.66)*

0.56 (0.46, 0.67)*

0.44 (0.32, 0.82)*

Time Slope

Visit

0.55 (0.49, 1.06)

0.66 (0.61, 1.35)

1.76 (1.53, 1.94)*

cART: After initiation

1.62 (1.34, 1.91)***

1.67 (1.39, 2.01)**

2.10 (1.45, 3.04)**

Physical health score

1.02 (1.01, 1.03)**

1.02 (1.01, 1.03)**

1.03 (0.99, 1.05)

Psychological well-being scores

1.01 (0.99, 1.02)

1.02 (1.01, 1.03)**

1.02 (1.01, 1.03)**

Level of independence scores

1.02 (1.01, 1.04)*

1.02 (1.01, 1.04)*

1.02 (1.01, 1.04)*

Social relationship scores

1.01 (0,99, 1.01)

1.01 (1.003, 1.02)*

1.01 (0.99, 1.02)

Education: Grade 9–10

1.02 (0.97, 1.10)

1.04 (0.98, 1.12)

0.99 (0.91, 1.11)

Education: Grade  ≥11

1.03 (1.01, 1.07)*

1.10 (1.05, 1.15)**

1.01 (0.96, 1.06)

Age: 21–39 years

1.15 (1.01, 1.29)*

1.04 (1.01, 1.07)*

1.02 (0.94, 1.06)

Age: 40–59 years

1.04 (0.97, 1.09)

1.02 (0.96, 1.09)

1.11 (0.92, 1.42)

Marital status: Single/no sexual partners

0. 94 (0.89, 0.95)*

0.95 (0.88, 1.07)

1.02 (0.92, 1.09)

Marital status: Many sexual partners

0.91 (0.84, 0.99)*

0.96 (0.94, 0.99)*

1.07 (0.93, 1.27)

Sex while drunk: No

0.94 (0.92, 1.04)

1.04 (0.99, 1.08)

1.03 (0.97, 1.06)

Viral load

1.01 (0.99, 1.02)

1.01 (0.99, 1.03)

0.96 (0.93, 0.99)*

Weight

1.00 (0.99, 1.01)

1.00 (0.99, 1.01)

1.01 (0.99, 1.02)

Electrolyte component

1.02 (1.003, 1.07)*

1.01 (1.001, 1.04)*

1.00 (0.99, 1.02)

RBC indices component

1.01 (0.99, 1.02)

1.02 (1.01, 1.03)*

1.02 (0.99, 1.04)

Mononuclear component

1.01 (0.99, 1.03)

0.99 (89, 1.01)

0.99 (0.97, 1.03)

Random components of non-proportional odds

Intercepts variance

12.21* (9.96, 15.12)

interpt-slope covariance

−0.36* (−0.49, − 0.22)

Variance (Time slope)

0.02* (0.01, 0.02)

Model Diagnosis

 

Proportional Odds

Non-Proportional Odds

−2 log L

8656.51

8426.78

Bayesian DIC

9732.43

9301.43

Deviance (dbar)

9367.12

9221.87

  1. Keys:- Statistical significance: (*) P < 0.05; (**) P < 0.01; (***) P < 0.001; Reference category: ART [Before initation]; Age [≤20 years]; Education [≤8 grade]; Marital status [Married]; Sex while drunk [Yes]