Skip to main content

Table 7 Head-to-head comparison of different diagnostic tests among all cases

From: Mycobacterial antigens in pleural fluid mononuclear cells to diagnose pleural tuberculosis in HIV co-infected patients

 

Culture +

Culture -

Microscopy+

Microscopy-

N-PCR+

N-PCR-

RT-PCR+

RT-PCR-

Cell wall antigen+

Cell wall antigen-

Hetero- geneous antigens+

Hetero-geneous antigens-

LAM+

LAM-

Secreted antigen+

Secreted antigen-

n = 13

n = 28

n = 4

n = 37

n = 18

n = 23

n = 2

n = 39

n = 14

n = 27

n = 17

n = 24

n = 15

n = 26

n = 14

n = 27

Microscopy+

3

1

              

Microscopy-

10

27

              

N-PCR +

10

8

4

14

            

N-PCR -

3

20

0

23

            

RT-PCR+

2

0

2

0

2

0

          

RT-PCR-

11

28

2

37

16

23

          

Cell wall antigen+

4

10

3

11

7

7

2

12

        

Cell wall antigen-

9

18

1

26

11

16

0

27

        

Heterogenous antigens+

7

10

3

14

9

8

2

15

7

10

      

Heterogenous antigens-

6

18

1

23

9

15

0

24

7

17

      

LAM+

7

8

2

13

9

6

2

13

8

7

9

6

    

LAM-

6

20

2

24

9

17

0

26

6

20

8

18

    

Secreted antigen+

5

9

3

11

7

7

2

12

9

5

10

4

9

5

  

Secreted antigen-

8

19

1

26

11

16

0

27

5

22

7

20

6

21

  

LAM or secreted antigen+

7

13

3

17

10

10

2

18

10

10

12

8

15

5

14

6

LAM or secreted antigen-

6

15

1

20

8

13

0

21

4

17

5

16

0

21

0

21

Any antigen+

9

19

4

24

13

15

2

26

14

14

17

11

15

13

14

14

Any antigen-

4

9

0

13

5

8

0

13

0

13

0

13

0

13

0

13

  1. N-PCR Nested PCR, RT-PCR Real time PCR