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Table 5 Proportion and grade of most frequent adverse events observed in each arm of the study

From: Pharmacokinetic study of two different rifabutin doses co-administered with lopinavir/ritonavir in African HIV and tuberculosis co-infected adult patients

ClinicalArm AArm B
Adverse EventsGradeAdverse EventsGrade
Grade 1Grade 2Grade 3Grade 4Grade 1Grade 2Grade 3Grade 4
Asthenia/fatigue5/941  3/721  
Headaches4/931  6/751  
anorexia7/97   3/73   
diarrhoea1/911  2/72   
Nausea/vomiting1/91   3/73   
Arthralgia1/9  1 5/7131 
Insomnia6/942  3/721  
vertigo5/941  0/7    
Skin rash5/941  2/711  
Death1/9   11/7   1
Laboratory
 Anaemia9/923227/73211
 Leukopenia3/93   1/71   
 Neutropenia1/91   2/711  
 Thrombopenia0/9    1/7 2  
 ALT elevated6/942  0/7    
 ASAT elevated7/961  3/73   
 Amylasemia elevated3/93   2/7 2  
 Bilirubinemia T elevated4/94   5/732