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Table 1 Characteristics at study enrollment of ART-naïve treatment eligible adults (≥ 18 years) living with HIV in Kenya and starting ART in 2014 according to enrollment D-dimer level, normal/low vs. high (N = 611)

From: Changes in D-dimer after initiation of antiretroviral therapy in adults living with HIV in Kenya

 

Total

Normal/low D-dimer

(< 500 ng/mL)

High D-dimer

(≥ 500 ng/mL)

 

N

%

N

%

N

%

p-value

611

100.0

300

49.1

311

50.9

 

Enrollment D-dimer, median (IQR)

516.4 (302.7–926.6)

301.7 (199.0–397-6)

912.8 (690.2–1446.2)

< 0.0001

Sex

 Male

211

34.5

117

39.0

94

30.2

0.02

 Female

400

65.5

183

61.0

217

69.8

 

Age (years), median (IQR)

34 (29–43)

34 (29–43)

34 (29–43)

0.86

 < 25

52

8.5

29

9.7

23

7.4

0.60

 25–40

384

62.9

186

62.0

198

63.7

 

 > 40

175

28.6

85

28.3

90

28.9

 

CD4+ cells/mm3, median (IQR)

326 (194–442)

335 (221–451)

319 (177–435)

0.17

 > 500

78

12.8

39

13.0

39

12.5

0.42

 350–500

186

30.4

98

32.7

88

28.3

 

 200–349

190

31.1

95

31.7

95

30.6

 

 < 200

156

25.5

68

22.7

88

28.3

 

 Missing

1

0.2

0

0.0

1

0.3

 

Viral load copies/mL, median (IQR)

113,500 (23,600-399,000)

82,200 (15,800-294,000)

159,000 (33,400-501,000)

0.0001

 < 1000 (<log 3.0)

30

4.9

18

6.0

12

3.9

0.01

 1000–9999 (log 3.0–3.9)

57

9.3

34

11.3

23

7.4

 

 10,000–99,999 (log 4.0- < 4.9)

201

32.9

107

35.7

94

30.2

 

 100,000-1000,000 (log 5.0–5.9)

255

41.7

116

38.7

139

44.7

 

 > 1000,000 (>log 6.0)

53

8.7

16

5.3

37

11.9

 

 Missing

15

2.5

9

3.0

6

1.9

 

BMI, median (IQR)

20.9 (18.9–22.9)

21.1 (19.1–22.9)

20.5 (18.6–23.0)

0.21

 Underweight (< 18.5)

114

18.7

48

16.0

66

21.2

0.17

 Normal (18.5–24.9)

425

69.6

219

73.0

206

66.2

 

 Overweight & Obese (≥25)

72

11.8

33

11.0

39

12.5

 

Current TB at study enrollment

31

5.1

9

3.0

22

7.1

0.02