Table 2 Median biomarker values at baseline and 6 months and mean change from baseline to 6 months among adults (≥ 18 years) starting ART in Kenya 2014 (N = 611)
From: Changes in D-dimer after initiation of antiretroviral therapy in adults living with HIV in Kenya
Baseline | 6 months | Change baseline to 6 months | ||||
|---|---|---|---|---|---|---|
Median (IQR) | Log median (IQR) | Median (IQR) | Log median (IQR) | Mean log10 change (95% CI) | p-value* | |
D-dimer (ng/mL) | 516.4 (302.7–926.6) | 2.7 (2.5–3.0) | 390.0 (236.6–656.9) | 2.6 (2.4–2.8) | −0.12 (−0.15, −0.09) | < 0.0001 |
Sex | ||||||
Male | 448.0 (245.7–872.1) | 2.7 (2.4–2.9) | 290.1 (199.0–539.3) | 2.5 (2.3–2.7) | − 0.15 (− 0.2, − 0.1) | 0.14 |
Female | 566.1 (347.9–953.4) | 2.8 (2.5–3.0) | 430.2 (279.6–714.7) | 2.6 (2.4–2.9) | − 0.10 (− 0.14, − 0.07) | |
Baseline log viral load cells/mL | ||||||
> 6.0 | 819.8 (466.8–1262.3) | 2.9 (2.7–3.1) | 397.8 (259.5–617.8) | 2.6 (2.4–2.8) | − 0.28 (− 0.37, − 0.19) | < 0.01 |
5.0–6.0 | 566.8 (320.2–970.4) | 2.8 (2.5–3.0) | 399.2 (246.1–723.3) | 2.6 (2.4–2.9) | − 0.13 (− 0.17, − 0.09) | |
4.0–4.9 | 461.8 (284.3–894.9) | 2.7 (2.5–3.0) | 410.3 (258.4–639.3) | 2.6 (2.4–2.8) | − 0.08 (− 0.13, − 0.03) | |
< 4.0 | 435.0 (258.7–683.1) | 2.6 (2.4–2.8) | 326.4 (199.0–590.6) | 2.5 (2.3–2.8) | − 0.08 (− 0.14, 0.01) | |
Baseline TB | ||||||
No | 495.9 (300.6–884.8) | 2.7 (2.5–2.9) | 390.2 (237.4–666.3) | 2.6 (2.4–2.8) | −0.10 (− 0.13, − 0.07) | < 0.0001 |
Yes | 1230.3 (465.1–2586.3) | 3.1 (2.7–3.4) | 297.3 (199.0–572.8) | 2.5 (2.3–2.8) | −0.43 (− 0.56, − 0.31) | |