Table 4 Cox regression analyses for hospitalization and mortality in the first year of ART according to urine-LAM result and TB diagnosis category among ART-naïve adults
| Â | Unadjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | P-value |
|---|---|---|---|---|
Hospitalization at 90 days | ||||
 No TB diagnosed | 1.0 | < 0.001 | 1.0 | 0.025 |
 Urine-LAM negative/TB diagnosed | 2.88 (1.55–5.35) |  | 1.97 (1.02–3.81) |  |
 Urine-LAM positive | 5.36 (2.51–11.46) |  | 3.09 (1.33–7.17) |  |
Hospitalization at one year | ||||
 No TB diagnosed | 1.0 | < 0.001 | 1.0 | < 0.001 |
 Urine-LAM negative/TB diagnosed | 3.35 (2.07–5.41) |  | 2.42 (1.45–4.06) |  |
 Urine-LAM positive | 5.95 (3.29–10.58) |  | 3.65 (1.89–7.06) |  |
Hospitalization at 90 days among those with microbiologically-confirmed TB (n = 79) | ||||
 Urine-LAM negative | 1.0 | 0.07 | 1.0 | 0.29 |
 Urine-LAM positive | 2.44 (1.00–5.93) |  | 1.75 (0.64–4.78) |  |
Hospitalization at one year among those with microbiologically-confirmed TB (n = 79) | ||||
 Urine-LAM negative | 1.0 | 0.019 | 1.0 | 0.16 |
 Urine-LAM positive | 2.49 (1.22–5.06) |  | 1.84 (0.80–4.27) |  |
Mortality at 90 days | ||||
 No TB diagnosed | 1.0 | < 0.001 | 1.0 | 0.015 |
 Urine-LAM negative/TB diagnosed | 1.23 (0.47–3.20) |  | 1.01 (0.37–2.74) |  |
 Urine-LAM positive | 7.67 (3.48–16.90) |  | 3.83 (1.52–9.66) |  |
Mortality at one year | ||||
 No TB diagnosed | 1.0 |  | 1.0 | 0.07 |
 Urine-LAM negative/TB diagnosed | 1 |  | 1.40 (0.74–2.67) |  |
 Urine-LAM positive |  |  | 2.60 (1.19–5.66) |  |
Mortality at 90 days among those with microbiologically-confirmed TB (n = 79) | ||||
 Urine-LAM negative | 1.0 | 0.016 | 1.0 | 0.07 |
 Urine-LAM positive | 4.95 (1.43–17.12) |  | 3.90 (0.91–16.72) |  |
Mortality at one year among those with microbiologically-confirmed TB (n = 79) | ||||
 Urine-LAM negative | 1.0 | 0.035 | 1.0 | 0.10 |
 Urine-LAM positive | 3.23 (1.17–8.90) |  | 2.84 (0.86–9.41) |  |