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Table 3 Estimated excess AIDS/death in the first year after HIV-diagnosis by country and region 2010–2016

From: Estimating the burden of HIV late presentation and its attributable morbidity and mortality across Europe 2010–2016

   

Non-late presenters

Late presenters

Difference LP versus non-LP

Country

Number included from COHERE/EuroSIDA

Mean follow-up in COHERE/EuroSIDA in the first 12 months following

HIV-diagnosis

1-year incidence of AIDS/deaths observed in COHERE/EuroSIDAa

1-year incidence of AIDS/deaths observed in COHERE/EuroSIDAa

Adjusted ratio of 1-year incidence of AIDS/deaths between LP and non-LPb

Estimated excess AIDS/deaths attributable to LP (difference LP – non-LP)d 2010–2016

 

n

mean PYFU

IR/1000 PYFU (95%CI)

IR/1000 PYFU (95%CI)

aIRR (95%CI)

n (95% CI)

Austria

920

0.89

4.7 (0.6–17.0)

63.3 (38.5–88.1)

10.20 (2.4–43.3)

44 (7–415)

Belarusc

94

0.98

4.2 (3.2–5.2)

37.7 (4.6–136.1)

9.3 (7.2–11.9)

169 (127–2754)

Belgium

747

0.84

2.8 (0.1–15.4)

79.4 (45.4–113.3)

25.4 (3.4–190.9)

250 (24–1152)

Denmark

635

0.83

7.9 (1.0–28.5)

61.8 (36.9–98.9)

4.2 (0.9–18.4)

17 (0–533)

Estoniac

65

0.98

4.2 (3.2–5.2)

86.6 (10.5–312.7)

9.3 (7.2–11.9)

47 (35–1768)

France

4531

0.68

2.5 (0.7–6.5)

59.8 (47.4–72.2)

19.2 (7.0–52.7)

661 (218–2581)

Germany

3774

0.83

4.4 (1.6–9.6)

58.6 (47.3–69.9)

11.1 (4.8–25.4)

353 (134–2408)

Greece

1829

0.82

5.0 (1.4–12.8)

43.0 (27.6–58.5)

7.5 (2.6–21.5)

82 (20–724)

Italy

6241

0.80

5.1 (2.5–8.8)

44.8 (36.7–53.0)

6.6 (3.6–11.9)

286 (134–2674)

The Netherlands

4680

0.84

5.4 (2.8–9.5)

69.8 (57.4–82.1)

9.9 (5.4–18.0)

163 (81–1490)

Polandc

179

0.99

4.2 (3.2–5.2)

8.8 (0.2–48.9)

9.3 (7.2–11.9)

102 (77–591)

Russiac

168

0.98

4.2 (3.2–5.2)

40.7 (8.4–118.9)

9.3 (7.2–11.9)

10,357 (7768-147,448)

Spain

7118

0.78

1.9 (0.7–4.2)

52.9 (43.8–62.0)

18.9 (8.3–43.2)

404 (165–1377)

Sweden

1830

0.81

7.9 (2.6–18.5)

32.7 (20.6–44.9)

3.7 (1.4–9.7)

24 (4–382)

Switzerland

998

0.82

5.4 (0.7–19.3)

25.0 (12.5–44.6)

5.2 (1.0–25.7)

34 (0–355)

United Kingdom

5208

0.72

5.4 (2.7–9.7)

37.6 (28.4–46.9)

5.1 (2.7–9.9)

382 (153–4252)

Ukrainec

187

0.98

4.2 (3.2–5.2)

59.2 (16.1–151.6)

9.3 (7.2–11.9)

2424 (1818-44,080)

Regione

Centralc

179

0.99

4.3 (3.3–5.4)

8.8 (0.2–48.9)

9.3 (7.2–11.9)

407 (306–2355)

Eastc

327

0.98

4.3 (3.3–5.4)

36.2 (18.7–63.2)

9.3 (7.2–11.9)

14,597 (10,947-109,680)

West

38,511

0.79

4.3 (3.3–5.4)

51.5 (47.9–55.2)

9.2 (7.2–11.9)

3030 (2273-19,934)

  1. aEstimated number of events among LP or non-LP was estimated by applying event rates from COHERE/EuroSIDA to the total number diagnosed HIV-positive in the whole country (incidence rate (PYFU) x mean follow-up (PYFU) x number of LP or non-LP in the whole country). bAdjusted for age, sex and HIV exposure group. cIn Belarus, Estonia, Poland, Russia and Ukraine there were no registered events among non-LP in EuroSIDA/COHERE. The IR and the aIRR given for these countries are the averages for all countries combined. dExcess events were estimated as clinical events in LP compared to non-LP. eAs defined by ECDC. Regional estimates are not summations of those estimated for each country. aIRR Adjusted Incidence Rate Ratio, CI Confidence interval, IR Incidence Rate, LP Late Presentation, PYFU Person years of follow-up