| One or more pDDI in study period n = 959 | No pDDI in study period n = 115 | p value* |
---|---|---|---|
Demographics | |||
Age | Â | Â | 0.477 |
17–30 | 316 (32.9) | 42 (36.5) |  |
31–40 | 403 (42.0) | 48 (41.7) |  |
41–50 | 203 (21.2) | 20 (17.4) |  |
51+ | 37 (3.9) | 5 (4.3) | Â |
Gender | Â | Â | 0.070 |
Male | 560 (58.4) | 57 (49.6) | Â |
Female | 399 (41.6) | 58 (50.4) | Â |
Baseline diagnostics and investigations | |||
CD4 (cells/mm3) | 18 (7–55) | 35 (16–209) | 0.040 |
Diagnosis of cryptococcal meningitis | Â | Â | <.001 |
No | 364 (38.0) | 105 (91.3) | Â |
Yes | 595 (62.0) | 10 (8.7) | Â |
Diagnosis of tuberculosis | Â | Â | 0.049 |
No | 852 (88.8) | 109 (94.8) | Â |
Yes | 107 (11.2) | 6 (5.2) | Â |
Diagnosis of malaria | Â | Â | 0.209 |
No | 946 (98.6) | 115 (100) | Â |
Yes | 13 (1.4) | 0 | Â |
GCS on admission | Â | Â | 0.003 |
15 | 588 (61.4) | 54 (47) | Â |
< 15 | 369 (38.6) | 61 (53) |  |
CSF QCC (log10CFU/mL) | 4.58 (2.9–5.4) | 0 (0–6.6) | 0.053 |
In-patient data | |||
Number of administered drugs | 7 (5–9) | 3 (2–4) | <.001 |
Days of stay in hospital | 16 (11–19) | 8 (4.5–13) | <.001 |