Gaps in the care cascade for screening and treatment of refugees with tuberculosis infection in Middle Tennessee: a retrospective cohort study

Table 3 Univariate and Multivariable Analysis of Factors Associated with TBI Treatment Initiation

	Univariate			Multivariable
	OR	95% CI	p	OR	95% CI	p
Elixhauser Comorbidity Index^a
No Comorbidity (Score = 0)	ref
Any Comorbidity (Score ≥ 1)	0.79	[0.60,1.05]	0.11
Diabetes^a
No	ref
Yes	0.68	[0.31,1.48]	0.34
Hypertension^a
No	ref
Yes	0.54	[0.33,0.88]	0.01	0.64	[0.37,1.10]	0.10
Liver Disease^a
No	ref
Yes	0.94	[0.54,1.65]	0.83
HIV^a
No	ref
Yes	1.17	[0.31,4.43]	0.82
Screening Test
Tuberculin Skin Test	ref
Interferon Gamma Release Assay	1.88	[1.33,2.67]	< 0.001	2.89	[1.59,5.27]	0.001
Year of Arrival
2012	ref
2013	2.17	[1.49,3.18]	< 0.001	1.14	[0.66,1.99]	0.64
2014	1.42	[0.96,2.12]	0.08	0.72	[0.39,1.33]	0.29
2015	1.41	[0.94,2.12]	0.09	0.66	[0.36,1.21]	0.18
2016	0.73	[0.47,1.14]	0.17	0.40	[0.21,0.74]	0.004
Family Size at Time of Entry
Single	ref
Family of 2–3	0.82	[0.58,1.14]	0.23	1.04	[0.71,1.52]	0.83
Family of > 3	0.73	[0.53,0.99]	0.04	1.03	[0.72,1.48]	0.87
Sex
Female	ref
Male	1.44	[1.09,1.89]	0.01	1.42	[1.06,1.89]	0.02
Region of Origin
Sub-Saharan Africa	ref			ref
South-eastern Asia	1.18	[0.85,1.66]	0.32	1.07	[0.75,1.54]	0.69
Southern Asia	0.97	[0.69,1.37]	0.86	1.05	[0.71,1.54]	0.82
Western Asia	0.76	[0.46,1.28]	0.30	0.98	[0.57,1.69]	0.93
Other	0.80	[0.40,1.61]	0.53	0.87	[0.42,1.78]	0.70
Smoking History
No	ref
Yes	0.8	[0.45,1.41]	0.44
Flu Shot Received
No	ref
Yes	0.95	[0.73,1.24]	0.73
Distance to TB Clinic, miles	0.92	[0.85,1.00]	0.04	0.91	[0.83,0.99]	0.04
Time to Appointment, days
Screened after 11 vs 28 days	0.96	[0.55,1.68]	0.90	1.01	[0.63,1.60]	0.98
Screened after 14 vs 28 days	0.96	[0.70,1.27]	0.71	1.02	[0.74,1.40]	0.91
Age^b	0.99	[0.98,1.00]	0.04	0.99	[0.98,1.00]	0.28

^aElixhauser Comorbidity Score and individual comorbidities were run in separate models
^bOdds expressed as change per one year increase in age

ISSN: 1471-2334