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Table 4 Risk factors for relapse and death in patients with Gram-negative bacteria catheter-related bloodstream infection

From: Microbial epidemiology and risk factors for relapse in gram-negative bacteria catheter-related bloodstream infection with a pilot prospective study in patients with catheter removal receiving short-duration of antibiotic therapy

Characteristics

Relapse

Death

Yes

(N = 9)

No

(N = 131)

p-value

Multivariate analysis

OR (95% CI), p-value

Yes

(N = 34)

No

(N = 106)

p-value

Multivariate analysis

OR (95% CI), p-value

Age

69

66

0.171

 

63

67

0.800

 

Sex

 Male

5

73

1.000

 

22

56

0.241

 

 Female

4

58

  

12

50

  

Charlson comorbidity index

7

5

0.075

 

5

6

0.694

 

Underlying diseases

 HIV infection

0

1

1.000

 

0

1

1.000

 

 Cancer

4

35

0.264

 

13

26

0.130

 

 Liver disease

0

10

1.000

 

4

6

0.256

 

 Renal disease

5

49

0.307

 

7

47

0.015a

0.630 (0.216–1.895) 0.420

 COPD

1

6

0.379

 

2

5

0.677

 

 Diabetes mellitus

6

43

0.066

 

7

42

0.062

 

 Hematological disease

1

11

0.565

 

6

6

0.071

 

 Cardiovascular disease

3

25

0.383

 

5

23

0.465

 

 Trauma

0

5

1.000

 

3

2

0.092

 

Immunocompromised status

2

30

1.000

 

11

21

0.160

 

Microbial etiology

 Monomicrobial

9

124

1.000

 

32

101

0.677

 

 Polymicrobial

0

7

  

2

5

  

Origin of infection

 Healthcare-associated

3

28

0.415

 

0

31

< 0.001a

266,606,914.2 (< 0.001-infinity) 0.998

 Nosocomial

6

103

  

34

75

  

ICU admission at onset of infection

1

70

0.017a

0.173 (0.005–6.394), 0.341

26

45

0.001a

1.803 (0.590–5.512) 0.301

Surgery at present admission

2

74

0.080

 

24

52

0.031a

0.763 (0.279–2.086) 0.598

Type of catheter

 Tunneled hemodialysis catheter

5

27

0.029a

10.023 (0.559–179.714), 0.118

1

31

0.001a

1.013 (0.074–13.929) 0.992

 Short-term central venous catheter or arterial catheter

2

79

0.036a

2.320 (0.072–74.855), 0.635

29

52

< 0.001a

2.214 (0.599–8.187) 0.233

 Long-term central venous catheter or port

2

25

0.684

 

4

23

0.317

 

Catheter management

 Catheter retention

7

4

< 0.001a

145.315 (12.665–1667.369), < 0.001a

4

7

0.462

 

 Catheter removal

2

127

  

30

99

  

Total duration of therapy

14

16

0.269

0.855 (0.623–1.172) 0.330

15

16

0.264

0.990 (0.923–1.062) 0.781

Duration of therapy after catheter removal

13

14

0.946

 

11

14

0.039a

 
  1. ap-value < 0.05
  2. Abbreviations: HIV human immunodeficiency virus, COPD chronic obstructive pulmonary disease, ICU intensive care unit
  3. Data were presented as count except age, Charlson comorbidity index, total duration of therapy, duration of therapy after catheter removal, which were presented as median