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Table 1 General, maternal and infant factors for infants with early onset sepsis during the NePeriQIPa trial, by antibiotic treatment group; Guideline (n = 1172) and Non-Guideline (n = 354)

From: Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal

Background characteristic

Guideline

n (valid %)

Non-guideline

n (valid %)

p-value

General factors

 Size of hospital

  Large (n = 998)

870 (87.2)

128 (12.8)

< 0.01

  Medium (n = 467)

261 (55.9)

206 (44.1)

  Small (n = 61)

41 (66.2)

20 (32.8)

 NePeriQIP triala

  Baseline (n = 467)

326 (69.8)

141 (30.2)

< 0.01

  Intervention (n = 970)

769 (79.3)

201 (20.7)

 Born at home

62 (6.5)

20 (6.1)

0.81

 Inborn infants

719 (82.3)

211 (66.7)

< 0.01

Maternal factors

 Maternal age in years, mean (SD)

24.5 (4.8)

24.8 (0.27)

0.27

 Disadvantaged casteb

276 (23.6)

58 (16.4)

< 0.01

 Caesarean section (elective & emergency)

47 (4.3)

21 (6.1)

0.16

Infant factors

 Admission weight, mean (SD)

2820 (612)

2841 (636)

0.58

 Gestational age, mean (SD)

38.5 (2.7)

38.9 (2.9)

0.06

 Apgar 5 min < 7

53 (8.8)

16 (7.7)

0.64

 Outcome (death or referral to higher centre)

96 (8.4)

39 (11.3)

0.10

  1. Missing data: Intervention (n = 89); Born at home (n = 242); Inborn (n = 336); Caesarean section (n = 89); Admission weight (n = 31); Gestational age (n = 616); Apgar 5 min (n = 716); Outcome (n = 39).
  2. aNepal Perinatal Quality Improvement Project
  3. bDalit and Muslim