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Table 2 Clinical presentation at the newborn unit for infants with early onset sepsis, by antibiotic treatment group; Guideline (n = 1172) and Non-Guideline (n = 354)

From: Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal

Characteristics of cases

Guideline

n (valid %)

Non-guideline

n (valid %)

p-value

Lethargy

167 (19.2)

39 (12.3)

< 0.01

Tachypnoea (> 60 breaths per minute)

357 (31.7)

61 (17.9)

< 0.01

Seizures

41 (4.6)

9 (2.8)

0.18

Grunting

134 (14.8)

13 (4.2)

< 0.01

Apnoea

19 (2.1)

2 (0.7)

0.13a

Fever (> 38 degrees Celsius)

494 (44.4)

120 (35.5)

< 0.01

Hypothermia (< 35.5 degrees Celsius)

9 (0.9)

4 (1.2)

0.75a

Severe chest indrawing

27 (3.1)

3 (1.0)

0.06a

Central cyanosis

31 (3.5)

3 (0.9)

0.02a

Severe jaundice (palms and soles yellow)

14 (1.66)

4 (1.26)

0.79

  1. aFisher exact test