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Table 3 Crude and adjusted odds for treatment of early neonatal sepsis according to World Health Organisation guidelines

From: Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal

 

cOR (95% CI)

aORa (95% CI)

p-value

Background characteristic

 Large volume hospital

5.08 (3.95—6.55)

5.03 (3.85—6.60)

< 0.01

 Medium volume hospital

0.21 (0.16—0.26)

0.21 (0.16—0.28)

< 0.01

 Small volume hospital

0.61 (0.35—1.05)

0.70 (0.40—1.23)

0.22

 Disadvantaged casteb

1.57 (1.15—2.15)

1.67 (1.21—2.30)

< 0.01

 Inborn infant

2.31 (1.73—3.09)

2.24 (1.66—3.03)

< 0.01

Clinical presentation

 Lethargy

1.69 (1.16—2.46)

1.60 (1.09—2.36)

0.02

 Tachypnoea (> 60 breaths per minute)

2.12 (1.57—2.89)

1.86 (1.34—2.60)

< 0.01

 Grunting

3.99 (2.22—7.16)

3.38 (1.87—6.10)

< 0.01

 Fever (> 38 degrees Celsius)

1.45 (1.13—1.87)

1.42 (1.09—1.85)

0.01

 Central cyanosis

3.79 (1.15—12.47)

3.32 (1.00—11.02)

0.05

  1. Abbreviations: cOR crude odds ratios, aOR adjusted odds ratios, CI confidence interval
  2. aAdjusted for time trend and Nepal Perinatal Quality Improvement Project
  3. bDalit and Muslim