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Table 7 Association of different factors with clustering of M. tuberculosis complex

From: Molecular epidemiology of clinical Mycobacterium tuberculosis complex isolates in South Omo, Southern Ethiopia

Characteristics

Total N (%)

Clustered N (%)

COR (95% CI)

P value

AOR (95% CI)

P value

Sex

 Female

64 (41.0)

46 (71.9)

1.00

 

NA

 

 Male

92 (59.0)

68 (73.9)

1.11 (0.54–2.27)

0.778

  

Age in years

 15–29

70 (44.9)

55 (78.6)

1.00

 

NA

 

 30–44

59 (37.8)

41 (69.5)

0.62 (0.28–1.38)

0.241

  

  > =45

27 (17.3)

18 (66.7)

0.55 (0.20–1.46)

0.227

  

TB Type

 PTB

130 (83.3)

92 (70.8)

1.00

 

NA

 

 EPTB

26 (16.7)

22 (84.6)

2.27 (0.73–7.04)

0.155

  

Medical history

 New cases

148 (94.9)

107 (72.3)

1.00

 

NA

 

 Retreat. Cases

8 (5.1)

7 (87.5)

2.68 (0.32–22.48)

0.363

  

Residential area

 Non-pastoral

70 (51.1)

48 (68.6)

1.00

 

1

 

 Pastoral

67 (48.9)

56 (83.6)

2.33 (1.03–5.30)

0.043

2.29 (0.82–6.35)

0.112

Major lineagesa

 EAI

35 (22.9)

30 (85.7)

1.00

 

1.00

 

 EA

105 (68.6)

78 (74.3)

0.48 (0.17–1.37)

0.170

0.59 (0.16–2.22)

0.439

 IO

10 (6.5)

4 (40.0)

0.11 (0.02–0.54)

< 0.006

0.24 (0.03–1.83)

0.169

 Lineage_7

3 (2.0)

2 (66.7)

0.33 (0.03–4.40)

0.404

0.22 (0.01–3.50)

0.110

SIT status

 Shared type

119 (76.3)

101 (84.9)

1.00

 

1.00

 

 Orphan

37 (23.7)

13 (35.1)

0.10 (0.04–0.22)

< 0.001

0.09 (0.04–0.25)

< 0.001

Lineagea

 Delhi/CAS

37 (26.6)

30 (81.1)

1.00

 

NA

 

 Haarlem

22 (15.8)

16 (72.7)

0.62 (0.18–2.17)

0.456

  

 URAL

22 (15.8)

15 (68.2)

0.50 (0.15–1.69)

0.264

  

 Ethiopia_2

32 (23.0)

28 (87.5)

1.63 (0.43–6.19)

0.470

  

 TUR

10 (7.2)

7 (70.0)

0.54 (0.11–2.65)

0.452

  

 Ethiopia_3

13 (9.4)

11 (84.6)

1.28 (0.23–7.14)

0.776

  

 Ethiopia_1

3 (2.2)

2 (66.7)

0.47 (0.04–5.90)

0.556

  
  1. aSub-categories having only singletons or clustered (based on strain clustering data using spoligotype patterns) were excluded from the regression analysis; NA: Not applicable; some abbreviations sued here were defined in the legend of Table 2