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Table 1 Comparisons of clinical characteristics of gram-negative bacteraemia between the follow-up blood culture (FUBC) and no-FUBC groups

From: Predictive scoring models for persistent gram-negative bacteremia that reduce the need for follow-up blood cultures: a retrospective observational cohort study

  FUBC-drawn (n = 1276) No FUBC-drawn (n = 205) p-value
Age, years (± SD) 68.85 (± 14.27) 69.2 (± 14.13) 0.744
Sex (M) 628 (49.2%) 117 (57.1%) 0.042*
Body weight (kg) 59.90 (± 11.56) 59.24 (± 12.62) 0.533
Comorbidity
 DM 404 (31.7%) 70 (34.1%) 0.519
 Liver cirrhosis 95 (7.4%) 17 (8.3%) 0.776
 ESRD on HD 2 (1.0%) 35 (2.7%) 0.154
 ESRD on PD 6 (0.5%) 0 (0.0%) 1.000
 Rheumatic disease 18 (1.4%) 1 (0.5%) 0.500
 Haematologic malignancy 136 (10.7%) 7 (3.4%) 0.001*
 Solid malignancy 361 (28.4%) 60 (29.4%) 0.802
 Solid organ transplantation 34 (2.7%) 5 (2.4%) 1.000
 Bone marrow transplantation 28 (2.2%) 1 (0.5%) 0.167
 Intravascular device 308 (24.1%) 19 (9.3%) 0.000*
 Neutropenia 127 (10.0%) 6 (2.9%) 0.002*
 High-dose steroid 24 (1.9%) 1 (0.5%) 0.239
Microorganism
Escherichia coli 722 (56.6%) 113 (55.1%) 0.705
Klebsiella pneumoniae 250 (19.6%) 45 (22.0%) 0.451
Pseudomonas aeruginosa 62 (4.9%) 7 (3.4%) 0.384
 AmpC-encoded Enterobacteriaceaea 100 (7.8%) 21 (10.2%) 0.237
Acinetobacter baumannii 24 (1.9%) 1 (0.5%) 0.239
 ESBL-producing 313 (24.5%) 32 (15.6%) 0.006*
 Other gram-negative 110 (8.6%) 17 (8.3%) 0.895
 PBSI 50 (3.9%) 8 (3.9%) 1.000
Hospital onset 328 (25.7%) 53 (25.9%) 1.000
Site of infection
 Urinary genital tract 502 (39.3%) 71 (34.6%) 0.217
 Liver abscess 56 (4.4%) 7 (3.4%) 0.583
 Biliary 303 (23.7%) 86 (42.0%) 0.000*
 Intra-abdominal 135 (10.6%) 18 (8.8%) 0.462
 Respiratory 56 (4.4%) 5 (2.4%) 0.255
 SSTI 13 (1.0%) 1 (0.5%) 0.707
 Catheter-related 40 (3.1%) 2 (1.0%) 0.109
 Bone and joint infection 12 (0.9%) 1 (0.5%) 1.000
 Cardiovascular 3 (0.2%) 0 (0.0%) 1.000
 CNS infection 3 (0.2%) 0 (0.0%) 1.000
 Primary bacteraemia 143 (11.2%) 10 (4.9%) 0.006*
In-hospital mortality 87 (6.8%) 18 (8.8%) 0.379
  1. SD Standard deviation, M Male, DM Diabetes mellitus, ESRD End-stage renal disease, HD Haemodialysis, PD Peritoneal dialysis, ESBL Extended-spectrum beta-lactamase, PBSI Polymicrobial bloodstream infection, SSTI Skin and soft tissue infection, CNS Central nervous system
  2. aAmpC-encoded Enterobacteriaceae includes Serratia marcescens, Providencia stuartii, Proteus vulgaris, Citrobacter spp., Enterobacter spp., and Morganella morganii
  3. *p < 0.05