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Table 3 Independent risk factors and assigned scores used to build the predictive scoring model for positive follow-up blood culture in gram-negative bacteraemia, according to eradicable and non-eradicable sources of infection

From: Predictive scoring models for persistent gram-negative bacteremia that reduce the need for follow-up blood cultures: a retrospective observational cohort study

Eradicable source of infection
  Beta-coefficient Odds ratio (95% CI) p-value Assigned score
ESBL-producing microorganism infection 1.001 2.720 (1.179–6.271) 0.019 + 1
CRBSI 1.374 3.95 (1.522–10.255) 0.005 + 1
Unfavourable treatment responsea 0.802 2.229 (1.262–3.937) 0.006 + 1
qSOFA score ≥ 2 on the day of FUBC 0.864 2.371 (1.034–5.438) 0.041 + 1
Effective antibiotics administration before the day of FUBC −1.007 0.365 (0.164–0.814) 0.014 −1
Adequate source control before the day of FUBC −1.983 0.138 (0.064–0.294) 0.000 −2
Non-eradicable source of infection
 ESRD on HD 1.406 4.081 (1.331–12.515) 0.014 + 1
 Unfavourable treatment responsea 0.802 2.229 (1.262–3.937) 0.006 + 1
 Effective antibiotics administration before the day of FUBC −2.015 0.133 (0.069–0.258) 0.000 −2
  1. CI Confidence interval, ESBL Extended-spectrum beta-lactamase, CRBSI Catheter-related bloodstream infection, qSOFA Quick sequential organ failure assessment, FUBC Follow-up blood culture, ESRD End-stage renal disease, HD Haemodialysis
  2. aUnfavourable treatment response was defined as positivity for at least 2 variables among the presence of fever, aggravated leucocytosis, and no decrease of C-reactive protein on the day of FUBC