Skip to main content

Table 4 Receiver operating characteristics and predictability of scoring models for positive follow-up blood culture in gram-negative bacteraemia, according to the various cut-off values

From: Predictive scoring models for persistent gram-negative bacteremia that reduce the need for follow-up blood cultures: a retrospective observational cohort study

  AUC (95% CI) Cut-off Sensitivity Specificity PPV NPV
Eradicable source of infectiona 0.861 (0.806–0.916) −2 88.5% 67.0% 27.7% 97.6%
−1 76.9% 82.1% 38.1% 96.1%
0 46.2% 95.6% 60.0% 92.6%
1 17.3% 99.3% 75% 90.63%
2 3.8% 100% 100% 87.9%
Non-eradicable source of infection 0.792 (0.724–0.861) −2 83.9% 58.4% 14.4% 97.6%
−1 58.9% 86.9% 27.3% 96.2%
0 39.3% 95.5% 42.3% 95.0%
1 3.6% 100.0% 100.0% 92.5%
  1. AUC Area under the curve, CI Confidence interval, PPV Positive predictive value, NPV Negative predictive value
  2. aGram-negative bacteraemia in which the primary source of infection could be removed, e.g. removal of a central venous catheter or other endovascular device, drainage of a dilated bile duct or hydronephrosis, surgical debridement of skin and soft tissue infection or osteomyelitis, drainage or removal of an intra-abdominal abscess, or drainage of empyema or a lung abscess