Table 1 Published cases of interstitial pneumonitis secondary to intravesical BCG
Reference | Case | Age | BCC treatment before onset | Time from final BCC treatment to onset | Time from final BCC treatment to dyspnea | Antituberculosis | Steroid | Other symptoms | Prognosis |
|---|---|---|---|---|---|---|---|---|---|
Diner [10] | 1 | 81 | 6 weeks + 4 weeks of maintenance | 1 day | 2 weeks | INH + RFP + EB | PSL 30 mg | Fever | Alive |
Cho [6] | 2 | 76 | Not specified | 7 months | 7 months | INH + RFP + EB | Pulse | Fever, pancytopenia | Alive |
Lyons [11] | 3 | 78 | 4 weeks | 6 h | 3 weeks | INH + RFP | PSL 40 mg | Fever, hepatitis | Alive |
Carrasco [12] | 4 | 73 | 8 times | 10 days | Not specified | Not specified | mPSL 40 mg | Fever, hepatitis | Alive |
Um [3] | 5 | 60 | 3 times | 3 weeks | 3 weeks | Not specified | cortisteroid | Fever, hepatitis | Alive |
Naoki [13] | 6 | 61 | 3 times | 1 week | 3 weeks | INH + RFP + EB | Pulse | Fever, hepatitis | Alive |
Nitta [14] | 7 | 60 | 6 times + maintenance BCG | 1 day | 2 weeks | INH + RFP + EB | Pulse | Fever | Alive |
Horinaga [15] | 8 | 61 | 3 times | Not specified | Not specified | INH + RFP + SM | Pulse | Fever, hepatitis | Alive |
Uetsuki [16] | 9 | 49 | 8 times+ 5 times | Not specified | Not specified | INH + RFP | Pulse | Fever, hepatitis | Alive |
Yamamoto [17] | 10 | 81 | 5 times | 1 week | 2 weeks | INH + RFP | Pulse | Fever | Died |
Davis [18] | 11 | 79 | 7 times | 1 week | 12 days | INH + RFP + EB | PSL 60 mg | Fever | Alive |
Tobiume [19] | 12 | 86 | 3 times | 6 days | 6 days | INH + RFP | Pulse | Fever | Alive |
Caravaca [20] | 13 | 81 | 1 time | 30 days | Not specified | INH + RFP + EB | Not used (TAC + EVL) | Fever | Alive |
Azumi [21] | 14 | 73 | 6 times + 2 times | Not specified | 50 days after admission | INH + RFP + EB | Pulse | Fever, nephromegaly | Died |
Kitani [22] | 15 | 85 | 3 times | The same day | The same day | Not used | PSL 250 mg | Fever | Alive |
Kazuaki [23] | 16 | 72 | 6 times | 1 weeks | 2 weeks | Not used | Pulse | nausea | Died |