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Table 1 Baseline characteristics for patients undergoing valve surgery for IE by age groups

From: Differences in mortality in patients undergoing surgery for infective endocarditis according to age and valvular surgery

 

All

< 60 years

60–75 years

≥75 years

 

Number

1767

735

766

266

 

Age, median (IQR)

63 [52.7, 71.6]

50 [41.4, 55.6]

67.7 [63.8, 71.3]

78.2 [76.3, 80.3]

< 0.001

Female, N (%)

471 (26.7)

177 (24.1)

198 (25.8)

96 (36.1)

0.0006

Medical history prior to IE admission, N (%)

 AMI

102 (5.8)

26 (3.5)

52 (6.8)

24 (9.0)

0.001

 Heart failure

220 (12.5)

56 (7.6)

116 (15.1)

48 (18.0)

< 0.001

 Afib

241 (13.6)

35 (4.8)

142 (18.5)

64 (24.1)

< 0.001

 Mitral valve disease

165 (9.3)

52 (7.1)

86 (11.2)

27 (10.2)

0.02

 Aortic valve disease

455 (25.7)

107 (14.6)

227 (29.6)

121 (45.5)

< 0.001

 CIED

71 (4.0)

16 (2.2)

34 (4.4)

21 (7.9)

< 0.001

 Prosthetic heart valve

228 (12.9)

51 (6.9)

104 (13.6)

73 (27.4)

< 0.001

 Renal disease

123 (7.0)

57 (7.8)

53 (6.9)

13 (4.9)

0.29

 Dialysis

28 (1.6)

12 (1.6)

14 (1.8)

< 4

0.48

 Peripheral vascular disease

149 (8.4)

34 (4.6)

78 (10.2)

37 (13.9)

< 0.001

 Cerebrovascular disease

158 (8.9)

38 (5.2)

80 (10.4)

40 (15.0)

< 0.001

 Cancer

191 (10.8)

44 (6.0)

104 (13.6)

43 (16.2)

< 0.001

 COPD

128 (7.2)

21 (2.9)

77 (10.1)

30 (11.3)

< 0.001

 Liver disease

57 (3.2)

28 (3.8)

24 (3.1)

5 (1.9)

0.31

 Diabetes

182 (10.3)

49 (6.7)

95 (13.1)

34 (12.8)

< 0.001

Medication six months prior to IE admission, N (%)

 Diuretics

543 (30.7)

120 (16.3)

301 (39.3)

122 (45.9)

< 0.001

 Beta blockade

409 (23.1)

100 (13.6)

223 (29.1)

86 (32.3)

< 0.001

 RAS inhibition

547 (31.0)

133 (18.1)

305 (39.8)

109 (41.0)

< 0.001

 Lipid lowering medication

428 (24.2)

82 (11.2)

243 (31.7)

103 (38.7)

< 0.001

 Corticosteroids

138 (7.8)

42 (5.7)

69 (9.5)

26 (9.8)

0.02

 Aspirin

367 (20.8)

70 (9.5)

175 (24.1)

104 (39.1)

< 0.001

 Anticoagulants

298 (16.9)

74 (10.1)

147 (20.2)

61 (22.9)

< 0.001

 Antibiotics

899 (50.9)

359 (48.8)

374 (51.4)

149 (56.0)

0.13

  1. IE infective endocarditis, IQR interquartile range, 25th and 75th percentile, AMI acute myocardial infarction, Afib atril fibrillation/flutter, CIED cardiac implantable electronic device, COPD chronic obstructive pulmonary disease, RAS renin-angiotensin system
  2. The percentages of the qualitative variables are shown in parentheses
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BMC Infectious Diseases

ISSN: 1471-2334

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