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Table 2 Algorithms (principal and alternative) to identify people receiving care for chronic HCV infection from the French National Health Data System

From: French hepatitis C care cascade: substantial impact of direct-acting antivirals, but the road to elimination is still long

 

Principal algorithm

Alternative algorithm

Items

Definitions

Modifications compared with principal algorithm

AT LEAST ONE MAJOR CRITERION DURING THE YEAR AMONG THE FOLLOWING:

 

HCV genotyping

≥ 1 reimbursement

 

HCV antiviral treatment

≥ 1 reimbursement for pegylated interferon and ribavirin (with at least one common delivery date) or for first or second generation DAAs

 

HCV RNA quantitative PCR

≥ 3 reimbursements

≥ 2

Hospitalization with a principal or related diagnosis of chronic hepatitis C

≥ 1 hospitalization with a principal or related diagnosis of chronic hepatitis C in medicine, surgery or obstetric services

 

Long-term disease (LTD) registration for chronic hepatitis C (“incident patients”)

New LTD registrations for chronic hepatitis C

 

OR

BOTH THE INTERMEDIATE CRITERION DURING THE YEAR:

 

HCV RNA quantitative PCR

2 reimbursements

1

AND AT LEAST ONE MINOR CRITERION DURING THE YEAR AMONG THE FOLLOWING:

≥ 2

 

Liver fibrosis assessment

≥ 1 reimbursement for liver biopsy, fibrosis, liver stiffness measurement or blood biomarkers

 

Long-term disease registration for chronic hepatitis C (“prevalent patients”)

Patients registered with LTD status, excluding those admitted during the year

 

Hospitalization with an associated diagnosis of chronic hepatitis C

≥ 1 hospitalization with an associated diagnosis of chronic hepatitis C in medicine, surgery or obstetric services

 
  1. Details of selected codes are provided in Additional file 3