Table 2 Definitions used to determine QFT conversion at visit 2 and visit 3
|  | Conversion definition 1a (< 0.35, ≥0.35) | Conversion definition 2 (< 0.2, ≥0.7) | Conversion definition 3 (< 0.2, ≥1.05) | Conversion definition 4 (< 0.2, ≥1.4) |
|---|---|---|---|---|
Eligible for analysis if negative at visit 1 | ||||
 Nil | ≤8.0 | ≤8.0 | ≤8.0 | ≤8.0 |
 TBAgNil | < 0.35 or < 25% Nil | < 0.2 or < 25% Nil | < 0.2 or < 25% Nil | < 0.2 or < 25% Nil |
 MitogenNil | ≥0.5 | ≥0.5 | ≥0.5 | ≥0.5 |
Positive at visit 2 and/or visit 3 | ||||
 Nil | ≤8.0 | ≤8.0 | ≤8.0 | ≤8.0 |
 TBAgNil | ≥0.35 & ≥ 25% of Nil & absolute increase of ≥0.35 IU/mlover baseline value | ≥0.7 & ≥ 25% of Nil | ≥1.05 & ≥ 25% of Nil | ≥1.4 & ≥ 25% of Nil |
Negative at visit 2 and/or visit 3 | ||||
 Nil | ≤8.0 | ≤8.0 | ≤8.0 | ≤8.0 |
 TBAgNil | < 0.35 or < 25% Nil | < 0.7 or < 25% Nil | < 1.05 or < 25% Nil | < 1.4 or < 25% Nil |
 MitogenNil | ≥0.5 | ≥0.5 | ≥0.5 | ≥0.5 |
or | ||||
 Nil | ≤8.0 |  |  |  |
 TBAgNil | ≥0.35 & ≥ 25% of Nil & absolute increase of < 0.35 IU/ml over baseline value |  |  |  |
 MitogenNil | ≥0.5 |  |  |  |
Indeterminate | all other values | all other values | all other values | all other values |