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Table 8 Increasing levels of HCW basic compliance with non-quarantined patients (Column 5) combined with select parameter combinations from Table 6 (Scenarios 6, 15, 18, 22, and 25). The five selected scenarios varied levels of antimicrobial stewardship and ward-room terminal cleaning using an increased level of HCW compliance with quarantined patients (100%). (Note that the decimal place in the scenario number indicates the varying levels of HCW basic compliance with non-quarantined patients while the whole number represents the original scenario number from Table 6)

From: Comparing intervention strategies for reducing Clostridioides difficile transmission in acute healthcare settings: an agent-based modeling study

Scenario number

Half-daily antibiotic probability

Targeted antib reduction scenario

Probability of sufficient cleaning

HCW basic compliance

Change from baseline median colonizations

Change from baseline median infections

6.0

0.27*

2

0.8

0.45*

-59.83%

-30.08%

6.1

0.27*

2

0.8

0.75

-60.87%

-29.94%

6.2

0.27*

2

0.8

1

-61.21%

-27.43%

15.0

0.243

2

0.8

0.45*

-63.42%

-30.17%

15.1

0.243

2

0.8

0.75

-63.97%

-29.32%

15.2

0.243

2

0.8

1

-64.38%

-28.96%

18.0

0.243

3

0.8

0.45*

-67.39%

-33.33%

18.1

0.243

3

0.8

0.75

-67.40%

-33.56%

18.2

0.243

3

0.8

1

-67.89%

-34.81%

22.0

0.216

2

0.2

0.45*

-66.35%

-30.60%

22.1

0.216

2

0.2

0.75

-67.04%

-30.38%

22.2

0.216

2

0.2

1

-67.01%

-29.99%

25.0

0.216

3

0.2

0.45*

-69.77%

-34.04%

25.1

0.216

3

0.2

0.75

-70.16%

-33.58%

25.2

0.216

3

0.2

1

-70.25%

-34.38%

  1. *Baseline value