Skip to main content

Table 3 Factors associated with placental malaria among women with sample for both diagnosis, 2010–2014, Dar es Salaam, Tanzania (n = 941)a, b

From: Factors associated with sub-microscopic placental malaria and its association with adverse pregnancy outcomes among HIV-negative women in Dar es Salaam, Tanzania: a cohort study

Characteristics

DNA PCR positive

Histopathology positive

OR [95% CI]

P-value

OR [95% CI]

P-value

Maternal age in years

  ≤ 24

Ref

 

Ref

 

  ≥ 25

1.20 [0.88, 1.64]

0.24

1.15 [0.79, 1.68]

0.46

Gestational age in weeksc

0.97 [0.92, 1.02]

0.23

1.08 [1.00, 1.15]

0.04

Employment

 Unemployed

Ref

 

Ref

 

 Employedd

0.72 [0.52, 1.00]

0.05

0.69 [0.47, 1.00]

0.05

 Other

1.08 [0.75, 1.57]

0.67

0.49 [0.28, 0.86]

0.01

Years of education

 0–7

2.21 [0.99, 4.97]

0.05

5.87 [1.25, 27.51]

0.02

 8–11

1.85 [0.80, 4.27]

0.15

6.48 [1.37, 30.68]

0.02

  ≥ 12

Ref

 

Ref

 

Wealth index

 1 (Lowest)

Ref

 

Ref

 

 2

0.78 [0.52, 1.18]

0.24

1.58 [1.00, 2.50]

0.05

 3

1.10 [0.77, 1.57]

0.62

0.91 [0.57 1.46]

0.69

 4 (Highest)

1.22 [0.82, 1.82]

0.33

1.53 [0.94, 2.48]

0.09

Number of previous pregnancies

 First

0.94 [0.71, 1.25]

0.69

1.11 [0.79, 1.55]

0.56

 Second

Ref

 

Ref

 

Uses fumigation or mosquito coils or net at night

 No

1.75 [1.05, 2.92]

0.03

1.45 [0.76, 2.74]

0.26

 Yes

Ref

 

Ref

 

Body mass index (kg/m2)

Underweight

0.33 [0.17, 0.62]

0.001

0.78 [0.44, 1.36]

0.38

 Normal

Ref

 

Ref

 

 Overweight or obese

1.21 [0.90, 1.63]

0.21

1.48 [1.03, 2.11]

0.03

Anemia status

 Not anemic (Hb ≥ 11.0 g/dL)

Ref

 

Ref

 

 Anemic (Hb < 11.0 g/dL)

1.59 [1.20, 2.11]

0.001

1.70 [1.22, 2.38]

0.002

  1. OR is an odds ratio
  2. CI is the confidence interval
  3. a The model was adjusted for the trial supplement regimen received
  4. b The weighted analysis was used to account for missing placenta samples for placental malaria diagnosis. Multinomial distribution with the nominal outcome, each PCR positive and histopathology positive were compared to negative for both tests
  5. c Gestational age at enrollment based on last menstrual period
  6. d Employed includes skilled, unskilled, and informal employment