Characteristic | All cases n (%) | Wild type in pncA gene n (%) | Mutation in pncA gene n (%) | Crude Prevalence ratio (95%CI) | Adjusted Prevalence ratio (95%CI) | P value |
---|---|---|---|---|---|---|
Gender | ||||||
 Male | 211 (65.1) | 136 (66.7) | 75 (62.5) | 1.0 | 1.0 | |
 Female | 113 (34.9) | 68 (33.3) | 45 (37.5) | 1.12 (0.84–1.50) | 11 (0.82–1.46) | 0.56 |
Age (years) | ||||||
 <40 | 153 (47.2) | 87 (42.6) | 66 (55.0) | 1.0 | 1.0 | |
 40–59 | 108 (33.3) | 69 (33.8) | 39 (32.5) | 0.84 (0.61–1.14) | 0.82 (0.60–1.11) | 0.20 |
 ≧60 | 63 (19.4) | 48 (23.5) | 15 (12.5) | 0.55 (0.34–0.89) | 0.56 (0.34–0.91) | 0.02 |
Residence in area within China | ||||||
 East of china | 104 (32.1) | 69 (33.8) | 35 (29.2) | 1.0 | NA | |
 Central of china | 162 (50.0) | 96 (47.1) | 66 (55.0) | 1.21 (0.87–1.68) | NA | |
 West of china | 58 (17.9) | 39 (19.1) | 19 (15.8) | 0.97 (0.61–1.54) | NA | |
Occupationv | ||||||
 Farmer | 202 (62.3) | 135 (66.2) | 67 (55.8) | 1.0 | NA | |
 Others | 122 (37.7) | 69 (33.8) | 53 (44.2) | 1.31 (0.99–1.74) | NA | |
Residence in area according to start DOTS implementation | ||||||
 In 2000 or later | 187 (57.7) | 112 (54.9) | 75 (62.5) | 1.0 | NA | |
 Before 2000 | 137 (42.3) | 92 (45.1) | 45 (37.5) | 0.82 (0.61–1.10) | NA | |
Number of previous treatments | ||||||
 0 | 132 (40.7) | 88 (43.1) | 44 (36.7) | 1.0 | ||
 1 | 107 (33.0) | 67 (32.8) | 40 (33.3) | 1.12 (0.80–1.58) | 1.17 (0.84–1.63) | 0.35 |
 More than 1 | 81 (25.0) | 47 (23.0) | 34 (28.3) | 1.26 (0.89–1.79) | 1.55 (0.90–1.84) | 0.18 |
 Unknown | 4 (1.2) | 2 (1.0) | 2 (1.7) | 1.50 (0.55–4.12) | 2.56 (1.72–3.82) | < 0.001 |
Previous pyrazinamide usage | ||||||
 Yes | 144 (44.4) | 93 (45.6) | 51 (42.5) | 1.0 | NA | |
 No | 180 (55.6) | 111 (54.4) | 69 (57.5) | 1.08 (0.81–1.44) | NA | |
Genotype | ||||||
 Non-beijing strain | 42 (13.0) | 32 (15.7) | 10 (8.3) | 1.0 | 1.0 | |
 Beijing strain | 230 (71.0) | 139 (68.1) | 91 (75.8) | 1.66 (0.95–2.92) | 1.84 (1.01–3.34) | 0.045 |
 No data | 52 (16.0) | 33 (16.2) | 19 (15.8) | 1.54 (0.80–2.94) | 1.64 (0.82–3.25) | 0.16 |