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Table 6 Univariate and multivariate logistic regression analysis of risk factors for postoperative infection in children with congenital heart disease

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter

 

Univariate analysis

Multivariate analysis

OR (95% CI)

P-value

OR (95% CI)

P value

Age (days)

Unit = 30

0.998 (0.993,1.003)

0.43

  

Gender

Female

1.000

   

Male

0.963 (0.756,1.227)

0.761

  

Preterm birth

No

1.000

   

Yes

0.989 (0.237,4.124)

0.988

  

History of cardiac surgery

No

1.000

   

Yes

2.741 (2.092,3.59)

< 0.001

  

STS risk grade

Unit = 1

2.07 (1.843,2.326)

< 0.001

1.38 (1.167,1.633)

< 0.001

Delayed sternal closure

No

1.000

   

Yes

9.268 (2.774,30.965)

< 0.001

  

BMI

5th–95th percentile

1.000

   

< 5th percentile

2.209 (1.671,2.922)

< 0.001

1.934 (1.377,2.715)

< 0.001

> 95th percentile

0.618 (0.287,1.331)

0.219

0.864 (0.37,2.017)

0.736

CPB time

Unit = 1

1.019 (1.016,1.021)

< 0.001

1.018 (1.015,1.022)

< 0.001

Aortic clamping time

Unit = 1

1.027 (1.024,1.031)

< 0.001

  

Lymphocyte count

Normal

1.000

   

< cut off value

4.097 (1.736,9.668)

0.001

  

>cut off value

0.735 (0.571,0.947)

0.017

  

Lymphocytes /WBC

Normal

1.000

   

< cut off value

3.243 (1.607,6.543)

0.001

3.818 (1.529,9.533)

0.004

>cut off value

0.714 (0.534,0.956)

0.024

0.959 (0.658,1.399)

0.829

Neutrophil count

Normal

1.000

   

< cut off value

0.956 (0.61,1.497)

0.843

  

>cut off value

1.889 (1.296,2.754)

0.001

  

Neutrophil /WBC

Normal

1.000

   

< cut off value

0.853 (0.634,1.148)

0.295

  

>cut off value

2.426 (1.223,4.814)

0.011

  

ALT

Normal

1.000

   

< cut off value

1.338 (0.824,2.171)

0.239

  

>cut off value

3.696 (1.974,6.921)

< 0.001

  

AST

Normal

1.000

   

>cut off value

1.911 (1.454,2.512)

< 0.001

1.546 (1.119,2.136)

0.008

ALP

Normal

1.000

   

>cut off value

0.596 (0.081,4.369)

0.61

  

Serum creatinine

Normal

1.000

   

< cut off value

0 (0,.)

0.98

  

>cut off value

10.22 (0.923,113.101)

0.058

  
  1. Note: CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell