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Table 1 Sociodemographic and clinical characteristics of the study population, stratified by HIV-1 subtype

From: HIV-1 CRF01_AE subtype and HIV-1 DNA level among patients with chronic HIV-1 infection: a correlation study

 

Total N = 373

CRF01_AE n = 188

Non-CRF01_AE n = 185

P-value

Sex n(%)

   

0.429

 Male

263 (70.5)

129 (68.6)

134 (72.4)

 

 Female

110 (29.5)

59 (31.4)

51 (27.6)

 

 Age years

35 (27–43)

35 (28–43)

36 (27–43)

0.893

Ethnic category n(%)

   

0.655

 Han

321 (86.1)

157 (83.5)

164 (88.6)

 

 Minority

52 (13.9)

31 (16.5)

21 (11.4)

 

Route of Transmission n(%)

   

0.002

MSM

120 (32.2)

65 (34.6)

55 (29.7)

 

Heterosexual

195 (52.3)

106 (56.4)

89 (48.1)

 

Others

58 (15.5)

17 (9.0)

41 (22.2)

 

Time between diagnosis and ART initiation (years)

0.26 (0.99–1.18)

0.32 (0.11–1.57)

0.22 (0.09–0.97)

0.245

Baseline HIV-1 DNA log10 copies/mL

3.0 (2.6–3.4)

3.19 (2.7–3.5)

2.95 (2.6–3.2)

0.000

Baseline plasma viral load log10 copies/mL

4.6 (4.2–5.1)

4.83 (4.4–5.2)

4.49 (3.8–4.9)

0.000

Baseline CD4+ T cell count cells/μL

214 (129–299)

193 (103–286)

246 (157–206)

0.001

Baseline CD8+ T-cell count cells/μL

788 (530–1080)

733 (526–1058)

835 (545–1113)

0.391

Baseline CD4/CD8 ratio

0.24 (0.15–0.37)

0.23 (0.11–0.35)

0.27 (0.18–0.41)

0.006

96-week HIV-1 DNA log10 copies/mL

2.53 (2.09–2.91)

2.63 (2.21–2.97)

2.39 (2.00–2.80)

0.002

  1. Continuous variables are expressed as median (interquartile range). Abbreviations: ART, Antiretroviral therapy; PBMCs, Peripheral blood mononuclear cells