Table 3 Association between clinical risk factors and achieving HIV-1 DNA < 2 log10 copies/106 PBMCs
Variables | Univariate | OR (95% CI) | Multivariate | |
|---|---|---|---|---|
OR (95% CI) | P-value | P-value | ||
Sex | ||||
 Male | 1 |  | 1 |  |
 Female | 1.758 (1.045–2.957) | 0.034 | 1.447 (0.725–2.885) | 0.294 |
Age years | ||||
 18–35 | 1 |  | 1 |  |
 36–50 | 1.439 (0.594–3.487) | 0.421 | 1.328 (0.499–3.534) | 0.570 |
  > 50 | 0.850 (0.335–2.159) | 0.733 | 0.801 (0.291–2.206) | 0.668 |
Transmission route | ||||
 Homosexual | 1 |  | 1 |  |
 Heterosexual | 2.789 (1.009–7.715) | 0.048 | 3.024 (0.983–9.302) | 0.54 |
 Others | 3.558 (1.345–9.407) | 0.011 | 2.961 (1.017–8.622) | 0.05 |
HIV-1 subtype | ||||
 CRF01_AE | 1 |  | 1 |  |
 Non-CRF01_AE | 1.554 (0.941–2.569) | 0.085 | 1.279 (0.721–2.266) | 0.400 |
Baseline CD4 T cell count cells/μL | ||||
  < 200 | 1 |  | 1 |  |
  > 200 | 4.903 (2.634–9.124) | 0.000 | 3.341 (1.712–6.520) | 0.000 |
Baseline CD4/CD8 ratio | ||||
  < 0.5 | 1 |  | 1 |  |
  > 0.5 | 1.948 (0.953–3.979) | 0.067 | 1.475 (0.663–3.282) | 0.341 |
Baseline HIV-1 DNA log 10 copies/106 PBMCs | 0.380 (0.261–0.555) | 0.000 | 0.489 (0.335–0.714) | 0.000 |
Baseline HIV-1 RNA log 10 copies/106 PBMCs | 0.758 (0.590–0.974) | 0.000 | 0.985 (0.722–1.344) | 0.923 |