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Table 4 Pooled resistance profile of enterococcal isolates in Ethiopia

From: Prevalence of Vancomycin resistant enterococci (VRE) in Ethiopia: a systematic review and meta-analysis

Antibiotics

No of studies

No of enterococci isolates tested, N

Pooled resistance N, (%)

95% CI

I2 (%)

P-value

Amoxicillin

2

203

115 (56.5)

49.6–63.2

0.00

0.382

Amox-clavulanate

2

225

71 (45.3)

13.9–80.9

92.37

<  0.001

Ampicillin

16

807

344 (44.5)

29.2–61.0

90.83

<  0.001

Chloramphenicol

12

777

188 (32.9)

20.8–47.8

87.24

<  0.001

Ceftriaxone

2

8

4 (50.0)

20.0–80.0

0.00

>  0.05

Ciprofloxacin

17

765

266 (36.5)

27.0–47.3

75.30

<  0.001

Clindamycin

4

224

59 (26.9)

21.5–33.2

0.00

0.478

Daptomycin

2

29

0.5 (3.2)a

0.5–19.7

0.00

0.974

Doxycycline

3

254

85 (55.1)

22.2–84.0

90.21

<  0.001

Erythromycin

14

780

374 (49.6)

36.5–62.7

86.19

<  0.001

Gentamycin

10

533

248 (37.7)

22.2–56.1

88.86

<  0.001

Linezolid

2

30

2 (9.9)

2.8–29.0

0.00

0.336

Nitrofurantoin

9

404

117 (31.5)

23.4–41.0

38.76

0.110

Norfloxacin

5

350

100 (39.9)

18.6–66.6

90.21

<  0.001

Penicillin

8

343

181 (60.7)

39.9–78.3

86.63

<  0.001

Streptomycin

3

179

74 (36.8)

10.4–73.1

91.62

<  0.001

Tetracycline

9

450

199 (53.7)

35.8–70.7

86.95

<  0.001

SXT

10

241

104 (39.1)

21.48–59.6

45.58

0.088

MDR - enterococci

20

825

543 (60.0)

42.9–75.0

90.27

<  0.001

  1. SXT Trimethoprim-Sulfamethoxazole, MDR Multidrug resistance
  2. a Continuity correction (0.5) is added to the study