Table 1 Association between LLV characteristics and virologic failure in the linear mixed-effect model and the Cox proportional hazards model (N = 2155)
LLV groupa | Case Number | Cox proportional hazards model | Linear mixed-effect model | ||
|---|---|---|---|---|---|
HR (95%CI) | p-value | Estimate (95%CI) | p-value | ||
<  50 (copies/ml) | 1320 | 1(reference) |  | 0(reference) |  |
50–200 (copies/ml) | 435 | 0.72(0.31–1.68) | 0.453 | 0.00(− 0.02–0.02) | 0.819 |
blipb | 318 | 0.68(0.26–1.80) | 0.438 | 0.00(− 0.02–0.01) | 0.765 |
3–6 (months)c | 47 | 1.58(0.37–6.80) | 0.541 | 0.02(−0.01–0.06) | 0.213 |
6–12 (months)d | 53 | 1.02(1.01–1.03) | 0.975 | −0.02(− 0.05–0.02) | 0.325 |
>  12 (months)e | 17 | 1.02(1.01–1.03) | 0.986 | −0.02(− 0.08–0.04) | 0.572 |
200–400 (copies/ml) | 150 | 1.90(0.81–4.43) | 0.139 | 0.03(0.00–0.06) | 0.045 |
blipb | 108 | 1.91(0.72–5.06) | 0.196 | 0.03(0.00–0.06) | 0.051 |
3–6 (months)c | 14 | 1.02(1.01–1.03) | 0.979 | −0.02(−0.10–0.06) | 0.637 |
6–12 (months)d | 17 | 2.12(0.28–15.99) | 0.468 | 0.04(−0.03–0.11) | 0.246 |
>  12 (months)e | 11 | 3.43(0.46–25.54) | 0.229 | 0.07(−0.01–0.16) | 0.094 |
400–1000 (copies/ml) | 119 | 5.93(3.13–11.23) | 0.000 | 0.12(0.09–0.15) | 0.000 |
blipb | 78 | 4.41(1.96–9.92) | 0.000 | 0.08(0.05–0.12) | 0.000 |
3–6 (months)c | 18 | 6.59(1.94–22.34) | 0.002 | 0.15(0.07–0.22) | 0.000 |
6–12 (months)d | 14 | 5.19(1.22–22.18) | 0.026 | 0.12(0.04–0.21) | 0.004 |
>  12 (months)e | 9 | 9.63(2.82–32.95) | 0.000 | 0.32(0.21–0.42) | 0.000 |
HLB > 1000 (copies/ml) | 131 | 2.84(1.27–6.34) | 0.011 | 0.04(0.01–0.07) | 0.005 |
blipb | 98 | 0.97(0.23–4.09) | 0.961 | 0.00(−0.03–0.03) | 0.883 |
3–6 (months)c | 16 | 6.20(1.46–26.27) | 0.013 | 0.11(0.04–0.19) | 0.003 |
6–12 (months)d | 11 | 9.74(2.82–33.66) | 0.000 | 0.25(0.17–0.34) | 0.000 |
>  12 (months)e | 6 | 7.52(1.01–55.84) | 0.049 | 0.15(0.03–0.27) | 0.012 |