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Table 3 Characteristics of pulmonary TB stratified according to number of lung lesions in Lima, Peru, 2017

From: Severe pulmonary radiological manifestations are associated with a distinct biochemical profile in blood of tuberculosis patients with dysglycemia

Characteristics

≥ 4 lesions

n = 68

<  4 lesions

n = 64

p-value

Age (years)-median (IQR)

34.89 (24.32–47.85)

27.93 (22.75–35.84)

0.03

Sex

  

1.00

Male

42 (60.9)

39 (60.0)

 

Female

27 (39.1)

26 (40.0)

 

Education

  

0.17

Elementary and secondary school

55 (79.7)

45 (69.2)

 

Higher education

14 (20.3)

20 (30.8)

 

Prior TB

14 (20.3)

2 (3.1)

< 0.01

BCG vaccination

64 (94.1)

60 (92.3)

0.74

Smoking

14 (20.6)

14 (21.5)

1.00

Smokers at home

5 (7.4)

6 (9.2)

0.76

Cannabis use

7 (10.3)

13 (20.0)

0.15

Illicit drug use

8 (11.8)

8 (12.3)

1.00

Alcohol use

33 (48.5)

36 (55.4)

0.49

Hypertension

6 (8.8)

1 (1.5)

0.12

Asthma

1 (1.5)

6 (9.2)

0.06

Renal disease

1 (1.5)

1 (1.5)

1.00

Slow healing

9 (13.2)

10 (15.4)

0.81

Metformin use

7 (10.8)

0 (0)

0.01

BMI (kg/m2)-median (IQR)

22.52 (20.28–25.22)

23.25 (20.68–25.39)

0.32

Waist circumference (cm) -median (IQR)

82 (77–88)

83 (75–88)

0.99

Hemoglobin (g/dL) -median (IQR)

11.5 (10.3–12.95)

12.4 (11.23–13.23)

0.03

FPG (mg /dL) -median (IQR)

100.7 (91.9–110.1)

90.5 (86.9–96.7)

< 0.01

HbA1c (%)- median (IQR)

5.3 (4.9–6)

5.1 (4.8–5.3)

< 0.01

OGTT (mg/dL) -median (IQR)

118 (97.1–136.6)

111 (90.3–127.5)

0.25

AFB smear

  

0.02

Negative

25 (36.8)

34 (52.3)

 

1+

13 (19.1)

14 (21.5)

 

2+

8 (11.8)

6 (9.2)

 

3+

18 (26.5)

10 (15.4)

 

Scanty

4 (5.9)

1 (1.5)

 

L-J culture

  

0.06

Negative

14 (21.5)

23 (35.9)

 

1+

30 (46.2)

32 (50.0)

 

2+

7 (10.8)

2 (3.1)

 

3+

5 (7.7)

2 (3.1)

 

Colonies

9 (13.8)

5 (7.8)

 

BD MGIT™ 960 System

  

0.55

Positive

36 (85.7)

28 (80.0)

 

Negative

6 (14.3)

7 (20.0)

 

MDR

6 (14.3)

3 (8.8)

0.72

Isoniazid-resistant

7 (16.7)

7 (20.6)

0.77

Rifampicin-resistant

7 (16.7)

4 (11.8)

0.75

Cough for more than 4 weeks

63 (91.3)

58 (89.2)

0.78

Hemoptysis

30 (43.5)

27 (41.5)

0.86

Fever

28 (40.6)

34 (52.3)

0.23

Dyspnea

39 (56.5)

48 (73.8)

0.05

Night sweats

39 (56.5)

37 (56.9)

1.00

No appetite

39 (56.5)

42 (64.6)

0.38

Lost weight

48 (69.6)

49 (75.4)

0.56

Fatigue

55 (79.7)

49 (75.4)

0.68

Polyuria

27 (39.1)

25 (38.5)

1.00

Polydipsia

31 (44.9)

32 (49.2)

0.73

  1. Data represent no. (%); IQR Interquartile range. BCG Bacillus Calmette–Guérin, BMI Body Mass Index, Hb Hemoglobin, FPG Fasting Plasma Glucose, HbA1c Glycated Hemoglobin, OGTT Oral Glucose Tolerance Test, AFB Acid-Fast Bacilli, L-J Löwenstein-Jensen, MDR Multi Drug Resistant. Hypertension, asthma, renal disease and anemia as defined by the World Health Organization as described in Methods. Prior TB: diagnosis of active tuberculosis before of this