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Table 5 Head-to-head comparison of different TB diagnostic tests, including Xpert Ultra and the MPT64 test among TB cases1

From: Diagnosis of extrapulmonary tuberculosis using the MPT64 antigen detection test in a high-income low tuberculosis prevalence setting

 

All TB cases

n = 31

 

MPT64 test performed

Microscopy performed

1-step PCR performed

Nested-PCR performed

Culture performed

 

n = 31

n = 27

n = 18

n = 11

n = 26

 

MPT64 test +

MPT64 test -

Micro-scopy +

Micro-scopy -

1-step PCR+

1-step PCR-

Nested-PCR+

Nested-PCR-

Culture +

Culture -

 

n = 10

n = 21

n = 6

n = 21

n = 6

n = 12

n = 7

n = 4

n = 16

n = 10

Microscopy +

2

4

        

Microscopy -

4

17

        

1-step PCR +

4

2

4

2

      

1-step PCR -

2

10

2

9

      

Nested-PCR +

5

2

1

3

1

0

    

Nested-PCR -

0

4

0

4

0

1

    

Culture +

3

13

4

12

5

7

2

2

  

Culture -

3

7

2

7

1

5

0

2

  

Xpert Ultra +

2

2

2

2

3

0

1

1

4

0

Xpert Ultra -

0

3

0

3

0

1

0

1

1

2

  1. Abbreviations: TB, tuberculosis; PCR, polymerase chain reaction
  2. 1TB cases include both microbiologically confirmed TB cases (n = 26) and clinically diagnosed TB cases (n = 5)