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Table 2 Patients’ clinical characteristics for validation set (n = 86)

From: Plasma Hsa-miR-92a-3p in correlation with lipocalin-2 is associated with sepsis-induced coagulopathy

Variables

Sepsis-induced coagulopathy (n = 34)

Sepsis alone (n = 52)

P-value

Sex, F/M

61.90%

62.50%

P = 0.983a

Age, years

59.56 ± 17.131

63.48 ± 17.927

P = 0.316b

Source of infection%

 Pulmonary

58.00% (29)

42.00% (21)

P < 0.001a

 Biliary system and pancreatic

45.50% (5)

54.50% (6)

P = 0.276a

 Peritonitis

78.90% (15)

21.10% (4)

P < 0.001a

 Urinary system

60.00% (3)

40.00% (2)

P = 0.380a

 Cerebral

0% (0)

100% (1)

P = 1.000a

SOFA scores

6.68 ± 3.67

6.04 ± 3.16

P = 0.393b

APACHE II scores

17.35 ± 7.88

16.60 ± 6.73

P = 0.635b

28-day mortality%

67.7% (21)

32.3% (10)

P < 0.001a

PLT (×10^9/L)

108.03 ± 91.99

211.10 ± 96.93

P < 0.001b

D-dimer (mg/dL)

7.12 (3.00, 18.24)

4.60 (2.38, 8.64)

P < 0.001c

APTT (s)

44.80 (38.10, 61.10)

35.75 (31.70, 43.23)

P < .001c

PT (s)

14.90 (13.48, 17.33)

12.75 (11.53, 13.88)

P < 0.001c

PA%

66.53 ± 17.89

81.10 ± 11.98

P < 0.001c

INR

1.26 (1.16, 1.47)

1.11 (1.03, 1.18)

P < 0.001c

Fbg (mg/dL)

275.13 ± 136.45

421.50 ± 173.30

P < 0.001b

TT (s)

20.00 (18.28, 24.88)

19.10 (17.98, 20.70)

P = 0.055c

Cr (mmol/L)

75.65 (52.90, 137.20)

74.25 (53.80, 127.65)

P = 0.575c

BUN (mmol/L)

10.12 (5.78, 14.07)

8.54 (5.06, 12.78)

P = 0.299c

  1. aχ2 test, bStudent’s t test, cMann-Whitney U test, SOFA Sequential organ failure assessment, APACHE II Acute physiology and chronic health evaluation, PLT Platelet, APTT activated partial thromboplastin time, PT Prothrombin time, PA Prothrombin activity, INR International normalized ratio, Fbg Fibrinogen, TT Thrombin Time, Cr Creatine, BUN Blood urea nitrogen