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Table 3 Patients’ clinical characteristics for gene sequencing (n = 30)

From: Plasma Hsa-miR-92a-3p in correlation with lipocalin-2 is associated with sepsis-induced coagulopathy

Variables

Sepsis-induced coagulopathy (n = 15)

Sepsis alone (n = 15)

P-value

Sex, F/M

4/11

8/7

P = 0.136a

Age, years

62.60 ± 13.91

65.13 ± 20.40

P = 0.694b

Cause of sepsis%

 Pulmonary infection

75% (9)

25% (3)

P = 0.025a

 Biliary system and pancreatic

20% (1)

80% (4)

P = 0.330a

 Peritonitis

40% (4)

60% (6)

P = 0.439a

 Urinary system

50% (1)

50% (1)

P = 1.000a

 Cerebral

0% (0)

100% (1)

P = 1.000a

SOFA scores

9.00 ± 4.33

6.21 ± 3.39

P = 0.060b

APACHE II scores

20.20 ± 8.19

15.59 ± 7.77

P = 0.125b

PLT (×10^9/L)

131.20 ± 87.78

156.87 ± 76.27

P = 0.400b

D-dimer (mg/dL)

13.94 ± 12.41

5.72 ± 5.49

P = 0.026b

APTT (s)

50.80 (39.70, 60.70)

34.90 (33.40, 53.20)

P = 0.062c

PT (s)

17.00 (14.20, 20.10)

12.90 (12.50, 18.00)

P = 0.022c

PA%

62.15 ± 19.45

70.51 ± 14.57

P = 0.193b

INR

1.51 ± 0.54

1.30 ± 0.29

P = 0.197b

Fbg (mg/dL)

294.60 (140.60, 340.80)

310.30 (254.50, 533.40)

P = 0.262c

TT (s)

21.50 (19.20, 114.45)

23.00 (18.70, 282.90)

P = 0.787c

Cr (mmol/L)

137.40 (74.05, 232.75)

129.56 (77.80, 301.15)

P = 0.967c

BUN (mmol/L)

11.32 ± 6.49

11.45 ± 6.38

P = 0.959b

  1. aχ2 test, bStudent’s t test, cMann-Whitney U test, SOFA Sequential organ failure assessment, APACHE II Acute physiology and chronic health evaluation, PLT Platelet, APTT Activated partial thromboplastin time, PT Prothrombin time, PA Prothrombin activity, INR International normalized ratio, Fbg Fibrinogen, TT Thrombin Time, Cr Creatine, BUN Blood urea nitrogen