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Table 1 Infectious disease work-up

From: Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy – a case report

Pathogen

DOS

Method

Specimen

Borna disease virus-1

21

PCR

CSF

Borrelia burgdorferi

10

Ig, AI

CSF, S

Chikungunya virus

10

Ig

S

Cryptococcus neoformans/gatti

10

PCR

CSF

Cytomegalovirus

2, 10

PCR, Ig, AI

CSF, S

Dengue virus

10, 11

Ig

S

Ebstein Barr virus

10

PCR, Ig, AI

CSF, S

Enterovirus

10

PCR

CSF

Escherichia coli K1

10

PCR

CSF

Flaviviruses

21

PCR

CSF

Haemophilus influenzae

10

PCR

CSF

Hepatitis A virus

10

Ig

S

Hepatitis B virus

10

Ig, Ag

S

Hepatitis C virus

10

Ig

S

Herpes simplex virus 1/2

2, 10

PCR, Ig, AI

CSF, S

Human herpes virus 6

10

PCR

S

Human immunodeficiency virus

10

Ig, Ag

S

Japanese encephalitis virus

11

Ig

S

Leptospira sp.

10

Ig

S

Listeria monocytogenes

10

PCR

CSF

Lymphocytic choriomeningitis virus

10

Ig

CSF, S

Measels virus

10

AI

CSF, S

Mycobacterium tuberculosis

17

QFT

B

Neisseria meningitidis

10

PCR

CSF

Parechovirus

10

PCR

CSF

Plasmodium sp.

19

RT, M

S

Rabies virus

10

PCR

CSF

Rift Valley virus

11

PCR, Ig

S

Rubella virus

10

AI

CSF, S

Sandfly fever virus

10

Ig

S

Streptococcus agalactiae

10

PCR

CSF

Streptococcus pneumonieae

10

PCR

CSF

Tick-borne encephalitis virus

10, 11

Ig

CSF, S

Treponema pallidum

2, 10

Ig

S

Trypanosoma brucei gambiense/rhodesiense

2

PCR, Ig

S

Trypanosoma cruzi

2

Ig

S

Varicella zoster virus

10

PCR, Ig, AI

CSF, S

Variegated squirrel bornavirus-1

21

PCR

CSF

West Nile virus

10, 11

Ig

S

Yellow fever virus

2, 9, 11, 17, 21

PCR, Ig

CSF, S, A

Zika virus

10

PCR, Ig

S

  1. Evaluated pathogens with negative findings
  2. DOS Days after onset of symptoms, Ig Serology, AI pathogen specific CSF/serum antibody index, S Serum, Ag Antigen-Test, QFT Quantiferon test, B Blood, RT Rapid test, M Microscopy, A autopsy tissue