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Table 1 Prevalence of cryptococcal antigenaemia (CrAg) by demographic and clinical characteristics

From: Prevalence and mortality of cryptococcal disease in adults with advanced HIV in an urban tertiary hospital in Sierra Leone: a prospective study

 

Total number tested for CrAg (% of total)

Number CrAg positive

Prevalence of CrAg % (95%CI)

P-value (Fisher’s exact)

Total

170

8

4.7 (2.4–9.2)

 

Sex

0.144

 Male

69 (40.6)

1

1.4 (0.2–10.0)

 

 Female

101 (59.4)

7

6.9 (3.3–14.0)

 

Age (years)

1.000

< 35

64 (37.6)

3

4.7 (1.5–13.9)

 

≥35

106 (62.4)

5

4.7 (1.9–11.0)

 

Admission status

0.287

 Outpatient

79 (46.5)

2

2.5 (0.6–9.8)

 

 Inpatient

91 (53.5)

6

6.6 (2.9–14.1)

 

CD4 (cells/mm3)

1.000

  < 50

96 (56.5)

5

5.2 (0.7–9.7)

 

  ≥ 50

74 (43.5)

3

4.1 (0.0–8.7)

 

Time since HIV diagnosis (days)

0.278

  < 90 “newly diagnosed”

86 (50.6)

6

7.0 (3.1–14.9)

 

  ≥ 90

84 (49.4)

2

2.4 (0.6–9.5)

 

Previous antiretroviral therapy (ART)a

0.468

 ART naïve or newly-initiated

91 (56.2)

6

6.6 (2.9–14.1)

 

ART experienced

71 (43.8)

2

2.8 (0.7–10.9)

 

On ART at time of recruitmenta

 

1.000

 Yes

43 (26.9)

2

4.7 (1.1–17.6)

 

 No

117 (73.1)

6

5.1 (2.3–11.1)

 
  1. a It was not possible to determine ART history for 8 participants (4.7%), or current ART status for 10 participants (5.9%); all of these were CrAg negative