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Table 3 Socio-demographic and clinical factors associated with severe adverse events

From: Adverse events in Chinese human immunodeficiency virus (HIV) patients receiving first line antiretroviral therapy

Characteristic at baselineCase/nCrude modelAdjusted model
OR(95%CI)POR(95%CI)P
Age, years
  < 5077/4281   
  ≥ 508/460.96(0.43–2.14)0.920  
Marital status
 Single/divorced/widowed63/3670.80(0.47–1.38)0.421  
 Married/common law marriage22/1071   
Years of Education
  ≤ 918/881.22(0.69–2.19)0.495  
  > 967/3861   
BMI, kg/m2
  < 2454/3511 1 
  ≥ 2431/1231.85(1.12–3.06)0.0161.77(1.03–3.02)0.038
CD4+, cells/mm3
  ≤ 19921/1201   
 200–34922/1450.84(0.44–1.62)0.843  
 350–49924/1241.13(0.59–2.16)0.656  
  ≥ 50018/851.27(0.63–2.56)0.509  
Viral load, cells/ml
  < 100,00064/3821 1 
  ≥ 100,00021/921.47(0.84–2.56)0.1751.55(0.86–2.81)0.148
Syphilis Status
 Yes24/1490.83(0.50–1.40)0.483  
 No61/3251   
Hepatitis Status
 Positive7/311.37(0.57–3.28)0.487  
 Negative78/4431   
WHO Clinical Stage
 I + II75/4331   
 III + IV10/411.54(0.72–3.28)0.262  
Pre-existing AE
 Yes78/4032.19(0.97–4.97)0.0600.96(0.39–2.34)0.924
 No7/711 1 
Pre-existing multiple AE
 Yes49/1673.13(1.93–5.06)< 0.0012.72(1.59–4.64)< 0.001
 No36/3071 1 
Pre-existing severe AE
 Yes18/365.54(2.74–11.19)< 0.0015.58(2.65–11.73)< 0.001
 No67/4381 1