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Table 2 Associations between different factors and US rates of mortality with sepsis in a multivariable model

From: The relation between prescribing of different antibiotics and rates of mortality with sepsis in US adults

 

Aged 18-49y

Aged 50-64y

Aged 65-74y

Aged 75-84y

Aged 85 + y

Fluoroquinolones (prescription per 1000 residents/y)

0.01 (− 0.04,0.07)

0.15 (− 0.15,0.45)

0.26 (− 0.4,0.92)

− 0.16 (− 1.77,1.45)

− 0.61 (− 4.52,3.3)

Penicillins (prescription per 1000 residents/y)

− 0.03 (− 0.07,0)

0.08 (− 0.1,0.25)

0.11 (− 0.28,0.5)

0.95 (0.02,1.88)

2.97 (0.72,5.22)

Cephalosporins (prescription per 1000 residents/y)

0.05 (0.02,0.09)

0.07 (− 0.11,0.25)

0.13 (− 0.28,0.55)

−0.06 (− 1.04,0.93)

−0.76 (− 3.09,1.58)

Macrolides (prescription per 1000 residents/y)

0.02 (− 0.02,0.06)

0.06 (− 0.15,0.26)

0.21 (− 0.26,0.69)

0.45 (− 0.69,1.58)

0.71 (−2.03,3.45)

Median household income ($1000)

−0.06 (− 0.13,0.01)

−0.17 (− 0.55,0.2)

−0.09 (− 0.9,0.73)

0.54 (− 1.4,2.49)

1.95 (− 2.7,6.59)

Average minimal daily temperature (°F)

− 0.04 (− 0.11,0.03)

0.16 (− 0.19,0.51)

0.33 (− 0.44,1.1)

0.6 (− 1.26,2.46)

4.07 (− 0.55,8.7)

Percent African Americans

0.03 (− 0.05,0.11)

0.28 (−0.06,0.63)

1.25 (0.41,2.1)

2.68 (0.76,4.6)

3.02 (− 1.63,7.66)

Percent lacking health insurance

0.05 (−0.1,0.2)

0.95 (0.01,1.89)

ND

ND

ND

  1. Regression coefficients for the different covariates in the model given by eq. 1 for different age groups. The coefficients for the different antibiotic classes estimate the change in the annual rates of mortality with sepsis (per 10,000 individuals in a given age group) when the annual rate of outpatient prescribing of oral antibiotics in the corresponding class (per 1000 residents) increases by 1. ND = not done because persons aged > 64 years old are eligible for Medicare