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Table 4 Characteristics of children retained in care, dead or LTFU

From: A 17 year experience of attrition from care among HIV infected children in Nnewi South-East Nigeria

Characteristics

In care or referred

LTFU

Dead

p-value

Clinical stage at enrolment (n = 1101)

 WHO stage 1

75(13.3)

44(9.9)

3(3.2)

 

 WHO stage 2

161(28.5)

105(23.6)

9(9.7)

 

 WHO stage 3

297(52.7)

247(55.6)

53(57.0)

 

 WHO stage 4

31(5.5)

48(10.4)

28(30.1)

 

Duration of care

(n = 564)

(n = 457)

(n = 93)

 

  < 6 months

9(1.6)

192(42.0)

42(45.2)

 

 6 months to < 12 months

14(2.5)

66(14.4)

13(14.0)

 

 1 to < 5 years

165 (29.3)

137(30.0)

21(22.6)

 

 5 to < 10 years

227 (40.2)

48(10.5)

12(12.9)

 

 10 to < 15 years

145 (25.7)

14(3.1)

5(5.4)

 

  ≥ 15 years

4 (0.7)

0 (0.0)

0 (0.0)

 

 Median care duration (IQR) in years

6.9(6.3)

0.7(2.8)

0.6(3.3)

< 0.001*

Age at enrolment (years)

(n = 564)

(n = 457)

(n = 93)

 

  < 1 year

79(14.0)

84(18.4)

20(21.5)

 

 1 to < 5 years

198(35.1)

189(41.4)

36(38.7)

 

 5 to < 10 years

163(28.9)

121(26.5)

23(24.7)

 

 10 to < 15 years

124(22.0)

63(13.8)

14(15.1)

 

 Median enrolment age (IQR) in years

5.1(7.7)

3.8(6.0)

2.6(6.3)

< 0.001*

Age at last visit (years)

(n = 564)

(n = 457)

(n = 93)

 

  < 1 year

2(0.4)

43(9.4)

10(10.8)

 

 1 to < 5 years

33(5.9)

152(33.3)

30(32.3)

 

 5 < 10 years

104(18.4)

139(30.4)

25(26.9)

 

 10 to < 15 years

201(35.6)

105(23.0)

26(28.0)

 

  > =15 years

224(39.7)

18(3.9)

2(2.2)

 

 Median last visit age (IQR) in years

14.1(5.4)

6.0(7.7)

6.3(9.4)

< 0.001*

Use of ARV

 Yes

538 (95.4)

258(56.5)

70(75.3)

 

 No

26(4.6)

199(43.5)

23(24.7)

 

Enrolment and ARV initiation interval (months)

n = 538

n = 258

  

Mean ± SD

12.9 ± 25.84

6.7 ± 17.45

7.8 ± 16.51

< 0.001

ARV initiation and last visit interval (years)

n = 538

n = 258

n = 70

 

  < 1 year

40(7.4)

144(55.8)

39(55.7)

 

 1 to < 5 years

197(36.6)

72(27.9)

20(28.6)

 

 5 to < 10 years

199(37.0)

33(12.8)

7(10.0)

 

 10 years< 15 years

102 (19.0)

9 (3.5)

4 (5.7)

 

Median ARV initiation and last visit interval (IQR)

5.7(6.1)

0.6(3.0)

0.6(2.8)

<  0.001*

  1. LTFU loss to follow-up, IQR interquartile range, SD standard deviation, ARV anti-retrovirals
  2. *Statistically significant Kruskal-Wallis test, Statistically significant one-way ANOVA