Table 5 Result of bivariate and multivariate analysis of factors associated with attrition
From: A 17 year experience of attrition from care among HIV infected children in Nnewi South-East Nigeria
Variable | Total | PT Years | Attrition (%) | P-value | Estimated timeto event (years) | p-value | Attrition/1000PY | B | HR | P-value |
|---|---|---|---|---|---|---|---|---|---|---|
Total | 1114 | 5109.7 | 550(49.4) | 7.3 | 108 | |||||
Clinical stage | < 0.001c | |||||||||
WHO stage 1 | 122 | 646.1 | 47(38.5) | 11.5 | < 0.001 | 73 | −1.81 | 0.16(0.11–0.25) | < 0.001 | |
WHO stage 2 | 275 | 1488.2 | 114(41.5) | < 0.001a | 11.0 | 77 | −1.62 | 0.20(0.14–0.28) | < 0.001 | |
WHO stage 3 | 597 | 2767.0 | 300(50.3) | 6.7 | 108 | −0.96 | 0.39(0.29–0.52) | < 0.001 | ||
WHO stage 4 | 107 | 203.8 | 76(71.0) | 0.4 | 373 | – | Reference | – | ||
Use of ARVs | ||||||||||
Yes | 866 | 4762.9 | 328(37.9) | < 0.001a | 13.1 | < 0.001b | 69 | −2.13 | 0.12(0.09–0.15) | < 0.001c |
No | 248 | 346.8 | 222(89.5) | 0.5 | 640 | – | Reference | |||
Sex | 0.873 | |||||||||
Male | 547 | 2603.9 | 266(48.6) | 0.626 | 7.4 | 0.375 | 102 | 5.09 | 161.99 | 0.859 |
Female | 567 | 2505.8 | 284(50.1) | 6.7 | 113 | 5.04 | 154.27 | 0.860 | ||
Enrolment Age (years) | 0.001c | |||||||||
< 1 | 183 | 874.8 | 104(56.8) | 5.3 | 568 | 0.72 | 2.05 (1.40–3.00) | < 0.001c | ||
1 to < 5 | 423 | 2205.2 | 225(53.2) | 0.001a | 6.9 | 0.121 | 102 | 0.35 | 1.41 (1.02–1.96) | 0.037 |
5- < 10 | 307 | 1371.9 | 144(46.9) | 6.8 | 105 | 0.16 | 1.17(0.83–1.66) | 0.362 | ||
10 to < 15 | 201 | 657.8 | 77(38.3) | 7.3 | 117 | – | Reference | – | ||
Caregiver | 0.142 | |||||||||
Parent(s) | 718 | 3721.1 | 307(42.8) | 11.5 | 83 | −0.21 | 0.81 (0.49–1.34) | 0.417 | ||
Sibling | 13 | 46.8 | 1(7.7) | – | 21 | −1.65 | 0.19(0.03–1.45) | 0.109 | ||
Extended family member | 201 | 910.6 | 95(47.3) | 0.026a | 7.8 | 0.073 | 104 | −0.01 | 0.99(0.59–1.68) | 0.981 |
Others | 32 | 138.5 | 17(53.1) | 5.1 | 123 | – | Reference | – | ||
Place of residence | 0.577 | |||||||||
Same state ≤15 km radius | 162 | 810.9 | 79(48.8) | 0.058 | 8.1 | 0.065 | 97 | −0.21 | 0.81(0.49–1.34) | 0.299 |
Same state > 15 km from site | 820 | 3839.7 | 400(48.8) | 7.5 | 104 | −0.11 | 0.90(0.65–1.24) | 0.515 | ||
Other states | 132 | 459.1 | 71(53.8) | 3.9 | 155 | – | Reference | – | ||
Period of enrolment | < 0.001c | |||||||||
2003–2005 | 142 | 889.2 | 70(49.3) | 9.2 | 79 | −0.25 | 0.78(0.38–1.63) | 0.512 | ||
2006–2008 | 394 | 2300.7 | 194(49.2) | 8.3 | 0.001b | 84 | −0.67 | 0.51(0.25–1.04) | 0.063 | |
2009–2011 | 317 | 1171.7 | 186(58.7) | < 0.001a | 5.5 | 159 | −0.19 | 0.83(0.41–1.67) | 0.595 | |
2012–2014 | 137 | 499.8 | 58(42.3) | 5.2 | 116 | −0.05 | 0.95(0.46–1.97) | 0.897 | ||
2015–2017 | 76 | 191.4 | 29(38.2) | 3.5 | 152 | −0.00 | 1.00(0.46–2.20) | 0.997 | ||
2018–2019 | 48 | 57.0 | 13(27.1) | 2.0 | 228 | – | Reference | – | ||