Table 3 Laboratory results of patients with COVID-19 on hospital admission
From: Associated risk factors with disease severity and antiviral drug therapy in patients with COVID-19
Variables | All Patients (n = 550) | Severe (n = 178) | Non-severe (n = 372) | p value |
|---|---|---|---|---|
Blood tests, n/total n (%) | ||||
 Leucocytes (×109/L) | ||||
   < 4 | 119/502(23.7%) | 21/169(12.4%) | 98/333(29.4%) | < 0.001 |
  4–10 | 335/502(66.7%) | 110/169(65.1%) | 225/333(67.6%) | < 0.001 |
   > 10 | 48/502(9.6%) | 38/169(22.5%) | 10/333(3.0%) | < 0.001 |
 Neutrophil percentage (%) | ||||
  40–75 | 321/502(63.9%) | 47/169(27.8%) | 274/333(82.3%) | < 0.001 |
   > 75 | 175/502(34.9%) | 122/169(72.2%) | 53/333(15.9%) | < 0.001 |
 Lymphocyte percentage (%) | ||||
   < 20 | 230/502(45.8%) | 143/169(84.6%) | 87/333(26.1%) | < 0.001 |
  20–50 | 267/502(53.2%) | 26/169(15.4%) | 241/333(72.4%) | < 0.001 |
 Lymphocytes (×109/L) | ||||
   < 1.0 | 250/502(49.8%) | 130/169(76.9%) | 120/333(36.0%) | < 0.001 |
   ≥ 1.0 | 252/502(50.2%) | 39/169(23.1%) | 213/333(64.0%) | < 0.001 |
 Hemoglobin (g/L) | ||||
  Normal | 317/502(63.1%) | 108/169(63.9%) | 209/333(62.8%) | 0.802 |
  Decreased | 185/502(36.9%) | 61/169(36.1%) | 124/333(37.2%) | 0.802 |
 Platelets (×109/L) | ||||
   < 100 | 34/502(6.8%) | 13/169(7.7%) | 21/333(6.3%) | 0.559 |
   ≥ 100 | 468/502(93.2%) | 156/169(92.3%) | 312/333(93.7%) | 0.559 |
Inflammatory parameters-no./total no. (%) | ||||
 Procalcitonin (ng/ml) | ||||
   ≤ 0.1 | 279/393(71.0%) | 63/149(42.3%) | 216/244(88.5%) | < 0.001 |
   > 0.1 | 117/393(29.0%) | 86/149(57.7%) | 28/244(11.5%) | < 0.001 |
 hsCRP (mg/L) | ||||
   ≤ 3 | 120/404(29.7%) | 5/136(3.7%) | 115/268(42.9%) | < 0.001 |
   > 3 | 284/404(70.3%) | 131/136(96.3%) | 153/268(57.1%) | < 0.001 |
 ESR (mm/h) | ||||
   ≤ 15 | 74/185(40.0%) | 3/55(5.5%) | 71/130(54.6%) | < 0.001 |
   > 15 | 111/185(60.0%) | 52/55(94.5%) | 59/130(45.4%) | < 0.001 |
Myocardial enzyme-no./total no. (%) | ||||
 CK-MB (ng/mL) | ||||
   ≤ 6.22 | 399/422(94.5%) | 130/146(89.0%) | 269/276(97.5%) | < 0.001 |
   > 6.22 | 23/422(5.5%) | 16/146(11.0%) | 7/276(2.5%) | < 0.001 |
 Troponin T (ng/ml) | ||||
   ≤ 0.014 | 331/438(75.6%) | 82/161(50.9%) | 249/277(89.9%) | < 0.001 |
   > 0.014 | 107/438(24.4%) | 79/161(49.1%) | 28/277(10.1%) | < 0.001 |
Heart Failure Indicator-no./total no. (%) | ||||
 BNP (pg/ml) | ||||
   ≤ 222 | 166/291(57.0%) | 43/128(33.6%) | 123/163(75.5%) | < 0.001 |
   > 222 | 125/291(43.0%) | 85/128(66.4%) | 40/163(24.5%) | < 0.001 |
Liver function-no./total no. (%) | ||||
 Alanine transaminase (IU/L) | ||||
   ≤ 50 | 443/511(86.7%) | 136/175(77.7%) | 307/336(91.4%) | < 0.001 |
   > 50 | 68/511(13.3%) | 39/175(22.3%) | 29/336(8.6%) | < 0.001 |
 Aspartate aminotransferase (IU/L) | ||||
   ≤ 40 | 393/511(76.9%) | 95/175(54.3%) | 298/336(88.7%) | < 0.001 |
   > 40 | 118/511(23.1%) | 80/175(45.7%) | 38/336(11.3%) | < 0.001 |
 Albumin (g/L) | ||||
   < 40 | 345/511(67.5%) | 163/175(93.1%) | 182/336(54.2%) | < 0.001 |
  40–55 | 166/511(32.5%) | 12/175(6.9%) | 154/336(45.8%) | < 0.001 |
Coagulation Function, n/total n (%) | ||||
 APTT (S) | ||||
  24.6–35.4 | 364/430(84.7%) | 136/158(86.1%) | 228/272(83.8%) | 0.532 |
   > 35.4 | 66/430(15.3%) | 22/158(13.9%) | 44/272(16.2%) | 0.532 |
 D-dimer (μg/ml) | ||||
   ≤ 0.243 | 182/364(50.0%) | 25/133(18.8%) | 157/231(68.0%) | < 0.001 |
   > 0.243 | 182/364(50.0%) | 108/133(81.2%) | 74/231(32.0%) | < 0.001 |
Electrolyte, n/total n (%) | ||||
 Potassium (mmol/L) | ||||
   > 5.3 | 39/504(7.7%) | 22/172(12.8%) | 17/332(5.1%) | < 0.001 |
  3.5–5.3 | 389/504(77.2%) | 109/172(63.4%) | 280/332(84.4%) | < 0.001 |
   < 3.5 | 76/504(15.1%) | 41/172(23.8%) | 35/332(10.5%) | < 0.001 |
 Sodium (mmol/L) | ||||
   < 137 | 72/504(14.3%) | 44/172(25.6%) | 28/332(8.4%) | < 0.001 |
  137–147 | 411/504(81.5%) | 115/172(66.8%) | 296/332(89.2%) | < 0.001 |
   > 147 | 21/504(4.2%) | 13/172(7.6%) | 8/332(2.4%) | < 0.001 |
Renal Function, n/total n (%) | ||||
 Creatinine (μmol/L) | ||||
   ≤ 111 | 480/508(94.5%) | 160/176(90.9%) | 320/332(96.4%) | 0.010 |
   > 111 | 28/508(5.5%) | 16/176(9.1%) | 12/332(3.6%) | 0.010 |
 GFR | ||||
   < 66 | 36/508(7.1%) | 24/176(13.6%) | 12/332(3.6%) | < 0.001 |
   ≥ 66 | 472/508(92.9%) | 152/176(86.4%) | 320/332(96.4%) | < 0.001 |
Arterial blood gas analysis, n/total n (%) | ||||
 PH | ||||
   < 7.35 | 23/338(6.8%) | 14/165(8.5%) | 9/173(5.2%) | < 0.001 |
  7.35–7.45 | 233/338(68.9%) | 90/165(54.5%) | 143/173(82.7%) | < 0.001 |
   > 7.45 | 82/338(24.3%) | 61/165(37.0%) | 21/173(12.1%) | < 0.001 |
 Oxygenation index | ||||
   < 100 | 26/338(7.7%) | 26/165(15.8%) | 0/173(0.0%) | < 0.001 |
  100–300 | 98/338(29.0%) | 98/165(59.4%) | 0/173(0.0%) | < 0.001 |
   > 300 | 214/338(63.3%) | 41/165(24.8%) | 173/173(100.0%) | < 0.001 |
 PCO2 (mmHg) | ||||
   < 35 | 73/338(21.6%) | 52/165(31.5%) | 21/173(12.1%) | < 0.001 |
  35–45 | 185/338(54.7%) | 90/165(54.6%) | 95/173(55.0%) | < 0.001 |
   > 45 | 80/338(23.7%) | 23/165(13.9%) | 57/173(32.9%) | < 0.001 |
 Lactic acid (mmol/L) | ||||
   ≤ 2.2 | 245/338(72.5%) | 114/165(69.1%) | 131/173(75.7%) | 0.172 |
   > 2.2 | 93/338(27.5%) | 51/165(30.9%) | 42/173(24.3%) | 0.172 |