Table 1 Univariate analyses of baseline characteristics of HIV/CM inpatients in the derivative cohort
Variable | Survivors | Non-survivors | p-value |
|---|---|---|---|
(n = 328) | (n = 58) | ||
Demographic characteristics | |||
 Age (years, IQR) | 43(34,52) | 54(44.8,65) | < 0.0001 |
 Male sex, n (%) | 263 (80.2%) | 40 (69.0%) | 0.055 |
Comorbidity and Complications | |||
 Cerebral infarction, n (%) | 14 (4.3%) | 5 (8.6%) | 0.182# |
 Liver cirrhosis, n (%) | 5 (1.5%) | 2 (3.4%) | 0.284# |
 Diabetes, n (%) | 17 (5.2%) | 5 (8.6%) | 0.351# |
 Tuberculosis, n (%) | 47 (14.3%) | 12 (20.7%) | 0.215 |
 Pneumocystis pneumonia, n (%) | 30 (9.1%) | 6 (10.3%) | 0.772 |
 Bacterial pneumonia, n (%) | 48 (14.6%) | 13 (22.4%) | 0.134 |
 Cytomegalovirus infection | 34 (10.4%) | 7 (12.1%) | 0.698 |
Clinical characteristic | |||
 Time from symptom onset to hospital admission (month, IQR) | 0.7(0.3,1.0) | 1(0.3,2.0) | 0.287 |
 Maximum body temperature (°C, IQR) | 37.8 (36.7,39.0) | 36.6 (36.7,38.3) | 0.213 |
 Stiff neck, n (%) | 24 (7.3%) | 17 (29.3%) | < 0.0001 |
 Impaired consciousness, n (%) | 28 (8.5%) | 22 (37.9%) | < 0.0001 |
 Headache, n (%) | 243 (74.1%) | 45(77.6%) | 0.572 |
 Seizures, n (%) | 25 (7.6%) | 7 (12.1%) | 0.298# |
 Weight loss, n (%) | 125 (38.1%) | 29 (50.0%) | 0.088 |
Laboratory data | |||
 CSF glucose (mmol/L, IQR) | 2.54 (1.9,3.2) | 2.25 (1.2,3.1) | 0.045 |
 Neutrophil count (109/L, IQR) | 3.4 (2.3,5.4) | 3.8 (2.1,6.3) | 0.419 |
 TBIL (μmol/L, IQR) | 9.2 (7.0,13.6) | 13.5 (9.0,19.7) | < 0.0001 |
 HGB (g/L, IQR) | 115.0 (98.0,130.0) | 108.0 (94.3126.0) | 0.235 |
 PLT (×  106 /L, IQR) | 186 (126.0,248.8) | 120 (82,202) | < 0.0001 |
 Urea (mmol/L, IQR) | 3.8 (3.0,5.5) | 4.9 (3.7,6.8) | 0.001 |
 Creatinine (μmol/L, IQR) | 59.1 (49.0,71.2) | 60.3 (49.1,75.6) | 0.787 |
 White blood cell count (109/L, IQR) | 4.6 (3.4,6.5) | 4.7(3.1,7.2) | 0.939 |
 CD4+ T-cell count (cells/μL, IQR) | 32.0 (13.0,77.3) | 29.0 (12.8,48.0) | 0.095 |
 HIV RNA (log10 copies/mL, IQR) | 5.1 (3.9,5.7) | 5.4 (4.9,5.9) | 0.009 |
 ICP (mm H2O, IQR) | 215.0 (160.0,328.0) | 360.0 (247.0,400.0) | < 0.0001 |
 ART at hospital admission, n (%) | 198 (51.3%) | 27(46.6%) | 0.500 |