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Table 1 Characteristics of studies included in the meta-analysis

From: Associations of immunological features with COVID-19 severity: a systematic review and meta-analysis

Author

Study Design

Country

Age (years)

Sample size (Severe)

Sample size (Mild)

Sample size

Sex (male %)

Chen G. 2020 [3]

Retrospective

China

56 (50–65)

11

10

21

17 (81%)

Chen R. 2020 [31]

Retrospective

China

56 ± 15

155

345

500

313 (57.1%)

Chi Y. 2020 [10]

Retrospective

China

46

8

22

30

/

Du R. 2020 [9]

Prospective

China

69 ± 8

21

42

63

30 (47.6%)

He R. 2020 [6]

Retrospective

China

49 (34–62)

69

135

204

79 (38.7%)

Jiang M. 2020 [12]

Retrospective

China

46 (17–88)

17

86

103

58 (56.3%)

Li S. 2020 [24]

Retrospective

China

46

26

43

69

40 (60.0%)

Liu Y. 2020 [32]

Retrospective

China

/

30

46

76

/

Ma J. 2020 [33]

Retrospective

China

62 (59–70)

17

20

37

20 (54%)

Pallotto C. 2020 [34]

Retrospective

Italy

65

13

25

38

19 (50.0%)

Qin C. 2020 [4]

Retrospective

China

58 (47–67)

27

17

44

235 (52%)

Sophie H. 2020 [5]

Retrospective

France

66

38

36

74

60 (81.1%)

Sun D. 2020 [15]

Retrospective

China

65

11

25

36

29 (80.5%)

Urra J.M. 2020 [35]

Retrospective

Spain

59

27

145

172

104 (60.5%)

Wan S. 2020 [13]

Retrospective

China

46

21

102

123

66 (53.7%)

Wang F. 2020 [18]

Retrospective

China

69 ± 9

14

14

28

21 (75%)

Zhang J. 2020 [19]

Retrospective

China

38 (32–57)

93

18

111

46 (41.4%)

Zhao Y. 2020 [7]

Retrospective

China

48

18

53

71

30 (42.3%)

Zheng Y. 2020 [36]

Retrospective

China

49

26

63

89

/

Zhou Y. 2020 [14]

Retrospective

China

42

5

12

17

6 (35.3%)

Zhu Z. 2020 [16]

Retrospective

China

51

111

16

127

45 (35.4%)

  1. Age is described as mean or mean ± SD or median (IQR)